[AsCNP_P20] Poster Session 20
Pain 2

Sat. Oct 12, 2019 4:40 PM - 6:10 PM Poster Hall (Multi-purpose Hall)

Chair: ‌Makoto TSUDA (Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Japan)

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4:40 PM - 4:45 PM

[AsCNP-P20-1] Associations between genetic polymorphisms on chromosome 14q32 and effects of opioid analgesics and chronic pain

^○Yoshihiko KOSAKI^{1, 2}, Daisuke NISHIZAWA¹, Hideko ARITA³, Kazuo HANAOKA³, Choku YAJIMA³, Masako ISEKI⁴, Jitsu KATO⁵, Setsuro OGAWA⁶, Ayako HIRANUMA^{1, 7}, Shinya KASAI¹, Junko HASEGAWA¹, Kyoko NAKAYAMA¹, Yuko EBATA¹, Yoshihiko KOUKITA², Tatsuya ICHINOHE², Masakazu HAYASHIDA^{1, 4, 8}, Ken-ichi FUKUDA⁹, Kazutaka IKEDA¹ (1. Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan, 2. Department of Dental Anesthesiology, Tokyo Dental College, Tokyo, Japan, 3. Department of Anesthesiology and Pain Relief Center, JR Tokyo General Hospital, Tokyo, Japan, 4. Department of Anesthesiology & Pain Medicine, Juntendo University School of Medicine, Tokyo, Japan, 5. Department of Anesthesiology, Nihon University School of Medicine, Tokyo, Japan, 6. Nihon University University Research Center, Tokyo, Japan, 7. Department of Surgery, Toho University Sakura Medical Center, Sakura, Japan, 8. Department of Anesthesiology, Saitama Medical University International Medical Center, Hidaka, Japan, 9. Department of Oral Health and Clinical Science, Tokyo Dental College, Tokyo, Japan)

4:45 PM - 4:50 PM

[AsCNP-P20-2] Association of a candidate locus for human opioid sensitivity identified in a genome-wide association study in patients undergoing laparoscopic-assisted colectomy with postoperative opioid requirements in patients undergoing painful cosmetic surgery

^○Rie INOUE^{1, 2}, Daisuke NISHIZAWA¹, Junko HASEGAWA¹, Kyoko NAKAYAMA¹, Ken-ichi FUKUDA³, Hiroyuki SUMIKURA², Masakazu HAYASHIDA^{1, 2, 4}, Kazutaka IKEDA¹ (1. Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan, 2. Department of Anesthesiology & Pain Medicine, Graduate School of Medicine, Juntendo University, Tokyo, Japan, 3. Department of Oral Health & Clinical Science, Tokyo Dental College, Tokyo, Japan, 4. Department of Anesthesiology, Saitama Medical University International Medical Center, Hidaka, Japan)

4:50 PM - 4:55 PM

[AsCNP-P20-3] Association between a protease-activated receptor 2 gene polymorphism and cold water immersion-induced pain sensitivity

^○Moe SOEDA^{1, 2}, Seii OHKA¹, Daisuke NISHIZAWA¹, Manabu SUNO³, Ken-ichi FUKUDA², Tatsuya ICHINOHE⁴, Kazutaka IKEDA⁴ (1. Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan, 2. Department of Oral Health and Clinical Science, Tokyo Dental College, Tokyo, Japan, 3. Graduate School of Medicine Dentistry and Pharmaceutical science, Okayama University, Okayama, Japan, 4. Department of Dental Anesthesiology, Tokyo Dental College, Tokyo, Japan)

4:55 PM - 5:00 PM

[AsCNP-P20-4] The development of a percutaneously absorbable preparation of oxycodone

^○Hidetoshi TAGE, Haruka SHIMODA, Aoi GOSHIMA, Suguru ITO, Midori SODA, Kiyoyuki KITAICHI (Lab. of Pharmaceutics, Department of Biomedical Pharmaceutics, Gifu Pharmaceutical University, Gifu, Japan)

5:00 PM - 5:05 PM

[AsCNP-P20-5] Paclitaxel, an anti-cancer drug, causes extracellular release of HMGB1, a pro-inflammatory and pro-nociceptive mediator, in Schwann cells derived from neonatal rat sciatic nerves

^○Fumiko SEKIGUCHI, Rika YAMASHITA, Hiroki YASUI, Atsufumi KAWABATA (Laboratory of Pharmacology and Pathophysiology, Faculty of Pharmacy, Kindai University)

5:05 PM - 5:10 PM

[AsCNP-P20-6] Endogenous thrombin plays a preventive role against oxaliplatin-induced peripheral neuropathy: involvement of thrombomodulin-dependent inactivation of HMGB1 by thrombin

^○Maho TSUBOTA¹, Ryotaro FUKUDA¹, Yusuke HAYASHI¹, Takaya MIYAZAKI¹, Shin UEDA¹, Masahiro NISHIBORI², Atsufumi KAWABATA¹ (1. Laboratory of Pharmacology and Pathophysiology Faculty of Pharmacy, Kindai University, Osaka, Japan, 2. Department of Pharmacology, Okayama University Graduate School of Medicine, Okayama, Japan)

5:10 PM - 5:15 PM

[AsCNP-P20-7] Involvement of HMGB1 in bortezomib-induced peripheral neuropathy in mice

^○Yuya IKEDA¹, Takaya MIYAZAKI¹, Maho TSUBOTA¹, Shiori TOMITA¹, Fumiko SEKIGUCHI¹, Masahiro NISHIBORI², Atsufumi KAWABATA¹ (1. Laboratory of Pharmacology and Pathophysiology, Faculty of Pharmacy, Kindai University, Osaka, Japan, 2. Department of Pharmacology, Okayama University Graduate School of Medicine, Okayama, Japan)