[AsCNP] Symposium
AsCNP » [AsCNP] Symposium
Sun. Oct 13, 2019 10:30 AM - 12:10 PM Room 16 (Heian)
Organizer / Chair: Lih-Chu CHIOU (Graduate Institute of Brain and Mind Sciences, Department of Pharmacology, College of Medicine, National Taiwan University, Taiwan), Co-chair: Hiroshi NAGASE (International Institute for Integrative Sleep Medicine, University of Tsukuba, Japan), Discussants: Akihiro YAMANAKA (Research Institute of Environmental Medicine, Nagoya University, Japan), Makoto TSUDA (Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Japan)
Orexin A and orexin B, also named “hypocretin 1” and “hypocretin 2,” are a pair of neuropeptides derived from prepro-hypocretin. Orexin-expressing neurons are limited, mostly in the perifonical area and lateral hypothalamus, however project widely throughout the central nervous system. Orexins are found to mediate various neuro-cognitive functions, depending on the distributions of the receptors, namely OX1 and OX2 receptors. Interestingly, orexins often work hand-in-hand with other neuropeptides in the CNS to execute their regulatory roles. Complexed neuropeptide network, with orexins holding the pivotal role, were previously reported in sleep, pain and reward regulations. Pathological conditions related to these processes, including narcolepsy, chronic pain and substance abuse, are unmet medical needs. In this symposium, 4 speakers are going to present their extensive works on the roles of orexins in sleep, pain and reward regulations. The scope encompasses the basic sciences underlying these discoveries, and the translational potentials of the orexin system in clinical setting.
10:30 AM - 10:55 AM
○Makoto HONDA1, 2 (1. Tokyo Metropolitan Institute of Medical Science, Japan, 2. Seiwa Hospital, Institute of Neuropsychiatry, Japan)
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10:55 AM - 11:20 AM
○Ming Tatt LEE1, 2, 3, Yu-Chun CHIU2, Hsin-Jung LEE2, Lih-Chu CHIOU2, 3, 4 (1. Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia, 2. Graduate Institute of Pharmacology, National Taiwan University College of Medicine, Taiwan, 3. Graduate Institute of Brain and Mind Sciences, National Taiwan University College of Medicine, Taiwan, 4. Graduate Institute of Acupuncture Science, China Medical University, Taichung, Taiwan)
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11:20 AM - 11:45 AM
○Yi-Hung CHEN1, Hsin-Jung LEE2, Ming Tatt LEE2, Ya-Ting WU1, Yen-Hsien LEE3, Ling-Ling HWANG3, Ming-Shiu HUNG4, Andreas ZIMMER5, Ken MACKIE6, Lih-Chu CHIOU2 (1. Graduate Institute of Acupuncture Science, China Medical University, Taiwan, 2. Department of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan, 3. Department of Physiology, College of Medicine, Taipei Medical University, Taipei, Taiwan, 4. Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Zhunan, Miaoli County, Taiwan, 5. Institute for Molecular Psychiatry, University of Bonn, Bonn, Germany, 6. Gill Center and the Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana, USA)
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11:45 AM - 12:10 PM
○Lih-Chu CHIOU1, 2, 3, Li-Wei TUNG1, Lu-Yang CHANG1, Guan-Ling LU1, Yen-Hsien LEE4, Lung YU6, Hsin-Jung LEE2, Shu-Fang TENG2, Ling-Ling HWANG4, 5, Ming-Shiu HUNG7, Ken MACKIE8, Andreas ZIMMER9 (1. Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taiwan, 2. Department of Pharmacology, College of Medicine, National Taiwan University, Taiwan, 3. Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taiwan, 4. Graduate Institute of Biomedical Science, Taipei Medical University, Taipei, Taiwan, 5. Department of Physiology, Taipei Medical University, Taipei, Taiwan, 6. Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, 7. Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Zhunan, Miaoli County, Taiwan, 8. Gill Center and the Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana, USA, 9. Institute for Molecular Psychiatry, University of Bonn, Bonn, Germany)
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