The 60th Annual Meeting of BSJ

Session information

Print

Academic Events » Symposium

1SAA Protein aggregation driven by dynamic solution environments

Wed. Sep 28, 2022 9:00 AM - 11:30 AM Room A (Hakodate Arena Budokan A)

Organizers:Norio Yoshida(Kyusyu Univ.),Kenji Sugase(Kyoto Univ.)

In cells, the solution environment is constantly changing due to varying concentrations of chemicals, mechanical stimuli, and electric fields. In recent years, it has become evident that intrinsically disordered proteins, which do not have specific conformations, undergo liquid-liquid phase separation and amyloid fibrillization in response to the ‘dynamic’ solution environment. This series of self-condensation processes is controlled by the protein-protein and protein-solvent interactions of intrinsically disordered proteins, which have dynamic conformations and solvation states. In this workshop, we will discuss the latest research on the self-condensation process of intrinsically disordered proteins and their future development.

9:24 AM - 9:44 AM

[1SAA-2] Mechanism of amyloid fibrillation of a protein driven by a flow

〇Kenji Sugase1, Daichi Morimoto2, Erik Walinda3 (1.Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, 2.Department of Molecular Engineering, Graduate School of Engineering, Kyoto University, 3.Department of Molecular and Cellular Physiology, Graduate School of Medicine, Kyoto University)

10:04 AM - 10:24 AM

[1SAA-4] Phase separation mechanism of HP1α by phosphorylation

〇Ayako Furukawa1, Kento Yonezawa2,3, Tatsuki Negami4, Yuriko Yoshimura5, Aki Hayashi5, Jun-ichi Nakayama5,6, Naruhiko Adachi2, Toshiya Senda2, Kentaro Shimizu4, Tohru Terada4, Nobutaka Shimizu2, Yoshifumi Nishimura1,7 (1.Grad. Sch. Med. Life Sci., Univ. Yokohama City, 2.IMSS, KEK,, 3.NAIST, CDG, 4.Grad. Sch. Agr. Life Sci., Univ. Tokyo, 5.NIBB, 6.SOKENDAI, 7.Grad. Sch. Integ. Sci. Life, Univ. Hiroshima)