Academic Events » Symposium

1SFP Biophysical responses and biochemical/chemical controlling of membranes for cellular regulation and future therapy

Wed. Sep 28, 2022 1:50 PM - 4:20 PM Room F (Hakodate Citizen Hall Mian HallA)

Organizers:Ikuhiko Nakase(Osaka Metropolitan Univ.),Hisaaki Hirose(Kyoto Univ.)

Biological membranes participate in responses for acceptance/rejection of stimulation and environmental changes from outside/inside cells, leading to signal transduction and cellular responses including e.g., cellular uptake, migration, proliferation, and cell death. The biophysical responses/mechanisms-based membrane controlling systems are highly anticipated to be next-generation therapeutic methodologies for further achievements of disease regulation such as cancers. In this proposal symposium, advanced research technologies and achievements of visualizing and controlling membrane traffic, structures, penetration, and shape-dependent cellular signaling from the fusion viewpoints of biophysics, molecular cell biology, chemistry, and chemical biology will be presented, and membrane-based therapeutic methodology will be discussed.

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1:50 PM - 1:55 PM

[1SFP-00] Opening Remarks

1:55 PM - 2:20 PM

[1SFP-1] Uptake mechanisms of cell-penetrating peptides

〇Christian Widmann¹ (1.University of Lausanne, Switzerland)

2:20 PM - 2:45 PM

[1SFP-2] Roles of membrane lipids in the organization of cell-cell adhestion structure

〇Junichi Ikenouchi¹ (1.Grad. Sch. Sci., Kyushu Univ.)

2:45 PM - 3:05 PM

[1SFP-3(2Pos198)] Mechanism study of antimicrobial peptide synergistic effects at the molecular level by combining spectroscopy and electrochemical methods

〇Yuge Hou¹, Kaori Sugihara¹ (1.Institute of Industrial Science, The University of Tokyo,)

3:05 PM - 3:25 PM

[1SFP-4] Biofunctional peptide-modified exosomes for intracellular delivery

〇Ikuhiko Nakase¹ (1.Grad. Sch. Sci., Osaka Metropolitan Univ.)

3:25 PM - 3:50 PM

[1SFP-5] Membrane shaping by the BAR domain superfamily proteins and the extracellular vesicles by the shedding of filopodia

〇Shiro Suetsugu^1,2,3 (1.Biological Science, Nara Institue of Science and Technology, 2.Data Science Center, Nara Institue of Science and Technology, 3.Digital Green-Innovation, Nara Institue of Science and Technology)

3:50 PM - 4:15 PM

[1SFP-6] Investigating the mechano-osmotic regulation of cell membrane tension using fluorescent membrane tension probes

〇Aurelien Roux^1,2 (1.Department of Biochemistry, CH-1211, University of Geneva, 2.NCCR Chemical Biology, CH-1211, University of Geneva)

4:15 PM - 4:20 PM

Session information