Academic Events » Symposium

2SEP Dynamic translation: from initiation to the end

Thu. Sep 29, 2022 1:50 PM - 4:20 PM Room E (Multi-purpose room B)

Organizers:Takehito Tanzawa(Osaka Unv.),ZhuohaoYang (The Univ. of Tokyo)

Translation on ribosomes is a fundamental biological phenomenon that requires strict spatiotemporal regulation and quality control. Since translation is a multi-step reaction, it is necessary to clarify the details of each step in order to understand its whole glance. Recently, with advancing and developing analytical methods such as structural analysis, single molecular imaging, and NGS, it has been uncovered that the translation cycle on ribosomes is regulated in various ways. In this symposium, we would like to have young researchers from different fields shed light on and discuss the dynamics of cis/trans-acting translational control on ribosomes from theoretical and experimental perspectives.

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1:50 PM - 2:00 PM

[2SEP-00] Opening Remarks

2:00 PM - 2:16 PM

[2SEP-1] Novel repressive role of eIF4A1 during mTORC1 inhibition

〇Yuichi Shichino¹ (1.RIKEN CPR)

2:17 PM - 2:33 PM

[2SEP-2(1Pos121)] Computational Analysis of the Start Codon Recognition Mechanism Based on Free Energy Landscape

〇Takeru Kameda¹, Katsura Asano^2,3,4, Yuichi Togashi^1,5 (1.Coll. Life Sci., Ritsumeikan Univ., 2.Div. Biol., Kansas State Univ., 3.HiHA, Hiroshima Univ., 4.Grad. Sch. Integ. Sci. Life, Hiroshima Univ., 5.RIKEN BDR)

2:34 PM - 2:50 PM

[2SEP-3(2Pos109)] Regulation mechanism of translation through the interaction of RNase T2 with ribosome

〇Atsushi Minami¹, Takehito Tanzawa², Zhuohao Yang³, Takashi Funatsu³, Takayuki Kato², Tomohisa Kuzuyama^1,4, Hideji Yoshida⁵, Tetsuhiro Ogawa^1,4 (1.Grad. Sch. Agri. and Life Sci., Univ. Tokyo, 2.IPR, Osaka Univ., 3.Grad. Sch. Pharm. Sci., Univ. Tokyo, 4.CRIIM, Univ. Tokyo, 5.Fac. Med., Osaka Med. Pharm. Univ.)

2:51 PM - 3:07 PM

[2SEP-4] High-speed AFM visualizes translational GTPase factor pool formed around the ribosomal P-stalk

〇Hirotatsu Imai^1,2, Toshio Uchiumi³, Noriyuki Kodera² (1.Fac. Med., Univ. Ryukyus, 2.Nano-LSI, Kanazawa Univ., 3.Fac. Sci., Niigata Univ.)

3:08 PM - 3:24 PM

[2SEP-5] The mechanical stability of SecM translation arrest

〇Zhuohao Yang¹, Ryo Iizuka², Takashi Funatsu¹ (1.Grad. Sch. Pharm. Sci., The Univ. Tokyo, 2.Dept. Biol. Sci., Grad. Sch. Sci., The Univ. Tokyo)

3:25 PM - 3:41 PM

[2SEP-6] Attempt to visualize the synthetic polypeptide during translational arrest

〇Takehito Tanzawa¹ (1.IPR., Osaka Univ.)

Cancelled

3:42 PM - 3:58 PM

[2SEP-7] Cancelled

〇Kevin Mac Alister Stapleton¹ (1.Grad. Sch. Frontier BioSci., Osaka Univ.)

3:59 PM - 4:15 PM

[2SEP-8] ER Redox shift through the ribosome translation

〇Ryo Ushioda^1,2 (1.Fac. of Life Sci., Kyoto Sangyo Univ., 2.Inst. for Protein Dynamics, Kyoto Sangyo Univ.)

4:15 PM - 4:20 PM

Session information