1SAA Protein aggregation driven by dynamic solution environments

[1SAA-1] ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures

〇Naotaka Sekiyama¹, Kiyofumi Takaba², Saori Maki-Yonekura², Ken-ichi Akagi³, Yasuko Ohtani¹, Kayo Imamura¹, Tsuyoshi Terakawa¹, Keitaro Yamashita⁴, Koji Yonekura², Takashi Kodama¹, Hidehito Tochio¹ (1.Dept. of Biophysics, Grad Sch. of Science, Kyoto Univ., 2.RIKEN SPring-8 Center, 3.NIBIO, 4.MRC Laboratory of Molecular Biology)