Photobiology: Optogenetics & Optical Control

[2Pos249*] Cryo-EM structural analysis of pump-like channelrhodopsin ChRmine and structure guided engineering

〇Koichiro Kishi¹, Yoon Kim², Masahito ¹, Masatoshi Inoue², Tsukasa Kusakizako³, Peter Wang², Charu Ramakrishnan², Eamon Byrne², Elina Thadhani⁴, Joseph Paggi⁴, Toshiki Matsui¹, Keitaro Yamashita⁵, takashi Nagata⁶, Masae Konno⁶, Sean Quirin², Maisie Lo², Tyler Benster², Tomoko Uemura⁷, Kehong Liu⁷, Mikihiro Shibata⁸, Norimichi Nomura⁷, Iwata So⁷, Osamu Nureki³, Ron Dror⁴, Keiichi Inoue⁶, Deisseroth Karl², Kato Hideaki¹ (1.Komaba Inst. Sci., Univ. Tokyo, 2.Dept. Bioeng., Stanford Univ., 3.Dept. Bio. Sci., Univ. Tokyo, 4.Dept. Comp. Sci., Stanford Univ., 5.MRC Lab. Mol. Biol., 6.ISSP Univ. Tokyo, 7.Dept. Cell Biol., Kyoto Univ., 8.Inst. Front. Sci. Init., Kanazawa Univ.)