The 61st Annual Meeting of the Biophysical Society of Japan

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Academic Events » Symposium

2SGP Holistic concepts in GPCR dynamics

Wed. Nov 15, 2023 2:00 PM - 4:30 PM Room G (Conference Room 232+233 (Bldg. 2, 3F))

Organizers: Katayama Kota (Nagoya Inst. of Tech.)、Suno Ryoji (Kansai Medical Univ.)

Tremendous advances in the structural biology and pharmacology of GPCRs, coupled with rapid advances in computational approaches, have expanded our understanding of both structural and functional aspects of GPCR dynamics and GPCR-ligand or partner protein interactions, providing guidance for new structure-based drug design. The goal of this symposium is to expose scientists to recent discoveries and cross-disciplinary approaches utilized to study GPCRs and provide opportunities for establishing communications that bridge complementary interests in the field of GPCRs. This session will feature speakers who have made exciting discoveries about the molecular mechanisms of GPCRs and partner proteins involved in signal transduction by utilizing spectroscopic, structural biology, single molecule observations, and computational chemistry approaches.

2:00 PM - 2:30 PM

[2SGP-1] Structural insights into human kappa opioid receptor signaling by biased ligand

〇Chiyo Suno-Ikeda1, Ryoji Suno1, Ryo Nishikawa2, Riko Suzuki3, Seiya Iwata2, Tomoyo Takai1, Takaya Ogura3, Mika Hirose4, Akitoshi Inoue1, Eri Asai1, Ryoji Kise3, Yukihiko Sugita5, Tsuyoshi Saito6, Kota Katayama2, Asuka Inoue3, Takayuki Kato4, Hiroshi Nagase6, Hideki Kandori2, Takuya Kobayashi1 (1.Dept. Med., Kansai Med. Univ,, 2.Grad. Sch. Eng., Nagoya Inst. Tech., 3.Grad. Sch. Pharm. Sci., Tohoku Univ., 4.IPR, Osaka Univ., 5.LiMe, Kyoto Univ., 6.IIIS, Tsukuba Univ.)