2023年11月15日(水) 08:50 〜 11:20 H会場 (会議室234（2号館 3F）)

オーガナイザー:炭竈 享司（JSTさきがけ）、岡崎 圭一（分子科学研究所）

Membrane transport proteins play essential roles in many physiological functions, such as maintenance of concentration gradients, nerve conductions, and synthesis of ATP. In principle, molecular motion should be involved in these functions, and observation of such molecular motion is necessary to fully understand their mechanisms. Recent computational simulations using high-performance computers have made it possible to fundamentally explain such functions at the molecular level. In this symposium, we will present recent advances in this field that help us understand (1) ion conduction and selectivity mechanism through the ion channels, (2) those through the ion pumps, (3) alternating-access conformational dynamics of transporters.