9:00 AM - 9:05 AM
Session information
Academic Events » Symposium
3SBA Biophysical approaches against the drug target proteins involving intrinsically disordered regions
Thu. Nov 16, 2023 9:00 AM - 11:30 AM Room B (Exhibition Room 212 (Bldg. 2, 1F))
Organizers: Hiroaki Hidekazu (Nagoya Univ.)、Shirai Tsuyoshi (Nagahama Inst. of Bio-Science and Tech.)
Recent progress in proteomics of human diseases and host-pathogen interactions has revealed that potential therapeutic targets contain intrinsically disordered regions (IDRs). Proteins with large amounts of IDRs often lack a fixed or ordered three-dimensional structure, rendering them unsuitable for the modern structure-guided drug discovery methodology. This symposium aims to explore different biophysical approaches to drug discovery and development against IDRs. We will focus on methods that go beyond the classical lock-and-key model, including innovative approaches to understand the structural and dynamic properties of IDRs.
9:05 AM - 9:25 AM
〇Hidekazu Hiroaki1,2,3 (1.Graduate School of Pharmaceutical Sciences, Nagoya University, 2.BeCellBar, LLC, 3.Center for One Medicine Innovative Translational Research (COMIT), Tokai National Higher Education and Research System)
9:25 AM - 9:55 AM
〇Chiaki Nishimura (1.Faculty of Pharmaceutical Sciences, Teikyo Heisei University)
9:55 AM - 10:20 AM
〇Akihito Nishiyama1, Masahiro Shimizu2,3, Noriyuki Kodera2, Yuriko Ozeki1, Kouta Mayanagi4, Takehiro Yamaguchi5, Sohkichi Matsumoto1 (1.Dept. Bacteriol., Niigata Univ. Sch. Med., 2.NanoLSI, Kanazawa Univ., 3.Div. Quantum Beam Mater. Sci., Inst. Integr. Radiat. Nuc. Sci., Kyoto Univ, 4.Med. Inst. Bioregulation, Kyushu Univ., 5.Dept. Pharmacol, Osaka Metro Univ. Med. Sch.)
10:20 AM - 10:45 AM
〇Masahiro Shimizu1, Ken Morishima1, Aya Okuda1, Rintaro Inoue1, Akihito Nishiyama2, Sohkichi Matsumoto2, Masaaki Sugiyama1 (1.KURNS., Kyoto Univ., 2.Dept. Bacteriol., Niigata Univ. Sch. Med.)
10:45 AM - 11:25 AM
〇Eiichiro Mori (1.Dept. Future Basic Med., Nara Med. Univ.)
11:25 AM - 11:30 AM