Thu. Nov 16, 2023 9:00 AM - 11:30 AM Room E (Conference Room 224 (Bldg. 2, 2F))

Organizers: Shimobayashi Shunsuke (Kyoto Univ.)、Kusumi Akihiro (OIST)

To understand how cells work, biophysicists are now discovering the mechanisms by which mesoscale subcellular molecular complexes are formed and function. This approach, particularly that using advanced microscopic imaging methods, is turning out to be very fruitful. Meso-scale, often between 3 and 300 nm, is an interesting spatial scale where non-living nano-scale molecules are assembled to start exhibiting the clear features of micron-scale living cells. Furthermore, recent research advances on the liquid condensates are further activating meso-scale investigations. Therefore, this symposium will focus on this very hot topic of meso-scale structures/events, including liquid signaling platforms, myosin-motor-driven cargo-membrane sculpting, subsynaptic meso-domains, DNA breaks, and fundamental material properties of biomolecular condensates. We hope to make this symposium a place where, together with the audience, new fundamentally important ideas emerge toward the understanding of how subcellular meso-scale structures form and function.