The 61st Annual Meeting of the Biophysical Society of Japan

Session information

Academic Events » Symposium

3SFA Biomolecular functions based on heterogeneous hydration dynamics

Thu. Nov 16, 2023 9:00 AM - 11:30 AM Room F (Conference Room 231 (Bldg. 2, 3F))

Organizers: Imashimizu Masahiko (AIST)、Hishida Masafumi (Univ. of Tsukuba)

How does a biomacromolecular complex like an enzyme work accurately and regulatory in water solvent system dominated by thermal fluctuations? The key to understand this question lies in the fact that, due to hydration, the thermal motions involved in biomolecular functions are temporally and spatially heterogeneous. For example, the collective intermolecular dynamics of protein and water molecules, which are overlapped in the sub-THz frequency region, may be relevant for expressing protein functions. In this symposium, we will attempt to discuss new directions regarding the unexplained phenomena in biomolecular functions based on the measurements of intermolecular dynamics, such as THz-TDS, fs-RIKES, microwave dielectric relaxation and NMR, and the physicochemical theoretical approach.