01A. Protein: Structure

[3Pos008] A novel activation mechanism of class B1 GPCRs via a conserved intracellular pocket

〇Kazuhiro Kobayashi¹, Kouki Kawakami¹, Tsukasa Kusakizako², Atsuhiro Tomita², Michihiro Nishimura², Kazuhiro Sawada², Hiroyuki Okamoto², Suzune Hiratsuka³, Gaku Nakamura³, Riku Kuwabara³, Hiroshi Noda⁴, Hiroyasu Muramatsu⁴, Masaru Shimizu⁴, Tomohiko Taguchi⁵, Asuka Inoue³, Takeshi Murata⁶, Osamu Nureki² (1.Komaba Institute for Science, the University of Tokyo, 2.Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 3.Graduate School of Pharmaceutical Sciences, Tohoku University, 4.Research Division, Chugai Pharmaceutical, 5.Laboratory of Organelle Pathophysiology, Department of Integrative Life Sciences, Graduate School of Life Sciences, Tohoku University, 6.Department of Chemistry, Graduate School of Science, Chiba University)