Poster 2

[PS2-84] The rational design of 2-(1H-benzo[d]imidazol-2-yl)-2-cyanovinyl derivatives as potent GyrB inhibitors against tuberculosis based on fragment molecular orbital calculations

*Naruedon Phusi¹, Yoshinobu Nagura², Bundit Kamsri¹, Bongkochawan Pakamwong¹, Paptawan Thongdee¹, Pharit Kamsri³, Auradee Punkvang³, Khomson Suttisintong⁴, Noriyuki Kurita², Pornpan Pungpo¹ (1. Ubon Ratchathani University (Thailand), 2. Toyohashi University of Technology (Japan), 3. Nakhon Phanom University (Thailand), 4. Thailand Science Park (Thailand))

Keywords:2-(1H-benzo[d]imidazol-2-yl)-2-cyanovinyl derivatives, GyrB inhibitors , M. tuberculosis, fragment molecular orbital calculations