^○Tomoko Kobayashi¹, So Sakai², Shunsuke Sawaguchi², Izumi Ishiyama³, Yoshifumi Kudo⁴, Atsushi Asai⁵ (1.Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan, 2.Tohoku University of Art &Design, Yamagata, Japan, 3.Tokoha University, Shizuoka, Japan, 4.Graduate School of Education, Tohoku University, Sendai, Japan, 5.Graduate School of Medicine, Tohoku University, Sendai, Japan)

^○Kazuya Itomi^1,4, Kato Mihoko^2,4, Kawamura Masayo^3,4, Horita Harihito¹ (1.Department of Neurology, Aichi Children's Health and Medical Center, Obu, Japan, 2.Department of Neurosurgery, Aichi Children's Health and Medical Center, Obu, Japan, 3.Department of Child and Adolescent Psychiatry, Aichi Children's Health and Medical Center, Obu, Japan, 4.Working Group for Promotion of Precious Promise Sharing, Aichi Children's Health and Medical Center, Obu, Japan)

^○Sho Hagiwara¹, Tadashi Shiohama¹, Satoru Takahashi³, Hironori Satou¹, Yusuke Kawasima², Daisuke Sawada¹, Tomoko Uchida¹, Chihiro Saitou¹, Hironobu Kobayashi⁶, Megumi Siota⁵, Hiromiti Hamada¹, Keiitirou Suzuki⁴ (1.Department of Pediatrics, University of Chiba, Chiba, Japan, 2.Kazusa DNA Resarch Institute, Chiba, Japan, 3.Departmento of Pediatrics, University of Asahikawa, Hokkaidou, Japan, 4.Institute for Advanced Co-Creation Studies, Universitu of Osaka, Osaka, Japan, 5.Department of Pediatrics, Tokyo women's Medical University Yachiyo Medical Center, Chiba, Japan, 6.Department of Pediatrics, Asahi general Hospital, Chiba, Japan)

^○Satomi Ohtaki^1,2, Hiromi Teranishi^1,2, Kaori Sassa^1,2, Hiroshi Matumoto^1,2, Fuyuki Miya³, Mitsuhiro Kato^4,5, Hideo Ymanouchi^1,2 (1.Department of Pediatrics, Saitama Medical University Hospital,Saitama,Japan, 2.Epilepsy center,Saitama medical university hospial,saitama,Japan, 3.Center for medical genetics, Keio Hospital,Tokyo,Japan, 4.Department of Pediatrics,Showa university,Tokyo,Japan, 5.Epilepsy center,Showa University,Tokyo,Japan)

^○Shunsuke Nomura¹, Yukako Kawasaki¹, Mituhide Nagaoka¹, Tomomi Inomata¹, Kentarou Tamura¹, Akiko Hiraiwa², Tomomi Tanaka^2,3, Rei Fukuda³, Hisato Suzuki⁴, Daisuke Watanabe⁴, Toshiki Takenouchi⁴, Taketosi Yosida¹ (1.Toyama Japan, 2.Toyama, Japan, 3.Toyama, Japan, 4.Tokyo, Japan)

^○Aritomo Kawashima¹, Kaori Kodama¹, Yu Katata¹, Wakaba Endo¹, Takehiko Inui¹, Noriko Togashi¹, Kazuhiro Haginoya¹, Shigeo Kure¹, Naomichi Matsumoto², Atsuo Kikuchi³ (1.Pedatric Neurology, Miyagi Children's Hospital, Sendai, Miyagi, Japan, 2.Deparment of Human Genetics, Yokohama City University, Yokohama, Kanagawa, Japan, 3.Department of Pediatrics, Tohoku University, Sendai, Miyagi, Japan)

^○Yoshiyuki Hanaoka¹, Yuko Chiba¹, Hisamichi Kunisawa¹, Yusuke Ogane¹, Takahiro Hayashi¹, Mariko Sawada¹, Akihito Takahashi¹, Shinsuke Ninomiya², Hisato Suzuki^3,4, Mamiko Yamada⁴, Toshiki Takenouchi⁴, Kenjiro Kosaki⁴, Kenji Waki¹ (1.Department of Pediatrics, Kurashiki Central Hospital, Okayama, Japan, 2.Department of Clinical Genetics, Kurashiki Central Hospital, Okayama, Japan, 3.Institute of Medicine, University of Tsukuba, Ibaraki, Japan, 4.Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan)

^○Yutaka Negishi¹, Kenji Kurosawa², Kyoko Takano³, Keiko Matsubara⁴, Takeshi Nishiyama⁵, Shinji Saitoh¹ (1.Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan, 2.Division of Medical Genetics, Kanagawa Children's Medical Center, Yokohama, Japan, 3.Center for Medical Genetics, Shinshu University Hospital, Matsumoto, Japan, 4.Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Tokyo, Japan, 5.Department of Public Health, Nagoya City University Graduate School of Medicine, Nagoya, Japan)

^○Rina Shimomura¹, Keiko Yamamoto^2,5, Mutsuki Nakano³, Takahiro Tayama³, Tatsuo Mori³, Ken Inoue⁴, Toshiyuki Yamamoto⁵ (1.Department of Pediatrics,Tokyo Women's Medical University,Tokyo,Japan, 2.Transfusion Medicine and Cell Processing,Tokyo Women's Medical University,Tokyo,Japan, 3.Department of Pediatrics,Tokushima University,Tokushima,Japan, 4.Department of Mental Retardation and Birth Defect Research,National Center of Neurology and Psychiatry,Tokyo,Japan, 5.Institute of Medical Genetics,Tokyo Women's Medical University,Tokyo,Japan)

^○Taiju Hayashi¹, Rei Urushibata¹, Hidetoshi Ishigaki¹, Takuya Hiraide¹, Hirotomo Saitsu², Tokiko Fukuda³ (1.Department of Pediatrics, Hamamatsu University School of Medicine,Hamamatsu,Japan, 2.Department of Biochemistry, Hamamatsu University School of Medicine,Hamamatsu,Japan, 3.Department of Hamamatsu Child Health and Development, Hamamatsu University School of Medicine,Hamamatsu,Japan)

^○Tatsuya Yamamoto¹, Hidenori Umetsu¹, Tatsuya Ito¹, Kiminori Terui¹, Mitsuhiro Kato², Hirotomo Saitsu³, Mitsuko Nakashima³, Sachiko Miyamoto³ (1.Department of Pediatrics, University of Hirosaki, Hirosaki, Japan, 2.Department of Pediatrics, University of Showa, Tokyo, Japan, 3.Biochemistry Department, Hamamatsu University School of Medicine, Hamamatsu, Japan)

^○Rei Urushibata¹, Takuya Hiraide¹, Taiju Hayashi¹, Hidetoshi Ishigaki¹, Tokiko Fukuda^1,2 (1.Department of Pediatrics, Hamamatsu University School of Medicine, Hamamatsu, Japan, 2.Hamamatsu Child Health and Developmental Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan)

^○Wataru Anzai¹, Nodoka Hinokuma¹, Tatsuya Suitou¹, Kozue Kobayashi¹, Kaori Yamoto², Mitsuko Nakashima², Hirotomo Saitsu², Mitsuhiro Kato^1,3 (1.Department of Pediatrics, Showa University, Tokyo, Japan, 2.Department of Biochemistry, Hamamatsu University School of Medicine, Hamamatsu, Japan, 3.Epilepsy Medical Center, Showa University, Tokyo, Japan)

^○Tatsuharu Sato¹, Risa Nakao¹, Asami Watanabe¹, Kohei Haraguchi¹, Shinji Saitoh² (1.The Department of Pediatrics, Nagasaki University Hospital, Nagasaki, Japan, 2.Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences)

^○Toshihiro Jogamoto, Chisato Yajima, Takahiro Motoki, Mariko Eguchi (Department of Pediatrics, Ehime University Graduate School of Medicine, Ehime, Japan)

^○Hideyuki Iwayama, Nami Nakamura, Mizuki Nishida, Shingo Numoto, Yoshiteru Azuma, Hirokazu Kurahashi, Akihisa Okumura (Department of Pediatrics, Aichi Medical University, Nagakute, Japan)

^○Daisuke Yamashita¹, Munetsugu Hara¹, Ryuta Ishii¹, Koutaro Yuge¹, Takayoshi Koike¹, Takehiko Fujino², Yushiro Yamashita¹ (1.The Department of Pediatriks and Child Health kurume University School of Medicine, 2.Institute of Rheological Functions of Food)

^○Koichi Tanda¹, Hidehito Kondo¹, Akira Nishimura¹, Takeshi Yoshida², Akira Inaba³, Takahito Wada³, Shinji Kosugi³, Mamiko Yamada⁵, Hisato Suzuki⁵, Toshiki Takeuchi⁴, Kenjiro Kosaki⁵ (1.Department of Pediatrics, Japanese Red Cross Kyoto Daiichi Hospital, 2.Department of Pediatrics, Kyoto University Graduate School of Medicine, 3.Clinical Genetics Unit, Kyoto University Hospital, 4.Department of Pediatrics, Keio University School of Medicine, 5.Center for Medical Genetics, Keio University School of Medicine)

^○Daisuke Uda¹, Masaharu Moroto¹, Tomoya Yodoi¹, Yoshihiro Nitta¹, Yohei Sugimoto², Tomohiro Chiyonobu³, Hiroyuki Yamada⁴, Kayo Ozaki⁵, Taichi Nakatani⁶, Norio Sakai⁷ (1.Department of Pediatrics, Fukuchiyama City Hospital, 2.Department of Pediatrics, Kumihama Hospital, 3.Department of Molecular Diagnostics and Therapeutics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 4.Department of Pediatrics, Toyooka Public Hospital, 5.Department of Endocrinology and Metabolism, Hyogo Prefectural Kobe Children's Hospital, 6.Department of Pediatric Surgery, Hyogo Prefectural Kobe Children's Hospital, 7.Division of Health Sciences, Osaka University Graduate School of Medicine)

^○Kohei Nagai¹, Hirokazu Yamagishi¹, karin Kojima¹, Ayumi Matsumoto¹, Waka Nakata², Kensuke Oka¹, Mitsuru Seki¹, Naoyuki Taga³, Kazuhiro Muramatsu¹, Hitoshi Osaka¹ (1.Department of Pediatrics, Jichi Medical University, Shimotsuke, Japan, 2.Pediatric Imaging Department, Jichi Medical University, Shimotsuke, Japan, 3.Pediatric Intensive Care Unit, Jichi Medical University, Shimotsuke, Japan)

^○Chihiro Saito¹, Tadashi Shiohama¹, Sho Hagiwara¹, Tomoko Uchida¹, Yuji Takahashi², Hidehiro Mizusawa³, Hiromichi Hamada¹ (1.Department of Pediatrics, Chiba University Hospital, Chiba, Japan, 2.Department of Neurology, National Center of Neurology and Psychiatry, Tokyo, Japan, 3.National Center of Neurology and Psychiatry, Tokyo, Japan)

^○Kohei Haraguchi¹, Akane Miyazaki¹, Asami Watanabe¹, Tastuharu Sato¹, Hiroyuki Mishima², Koh-ichiro Yoshiura², Sumito Dateki¹, Hiroyuki Moriuchi¹ (1.Department of Pediatrics, Nagasaki University Hospital, Nagasaki, Japan, 2.Department of Human Genetics, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan)

^○Yumi Okoshi¹, Chiemi Touhara², Masahiro Ito¹, Eriko Koshimizu³, Satoko Miyatake^3,4, Naomichi Matsumoto³ (1.Department of Pediatrics, Tokyo Metropolitan Fuchu Medical Center for the Disabled, Tokyo, Japan, 2.Department of Orthopedics, Tokyo Metropolitan Fuchu Medical Center for the Disabled, Tokyo, Japan, 3.Department of Genetics, Yokohama City University, Graduate School of Medicine, Kanagawa, Japan, 4.Department of Clinical Genetics, Yokohama City University Hospital, Kanagawa, Japan)

^○Moemi Hojo¹, Hitomi Fujii¹, Eijun Seki¹, Kei Yamada¹, Masaki Miura¹, Yu Kobayashi¹, Hiromi Nyuzuki^2,3, Takeshi Ikeuchi³, Yosuke Nishio^4,5, Taichi Oso^4,5, Tomoo Ogi^4,5, Jun Tohyama^1,3 (1.Department of Child Neurology, NHO Nishiniigata Chuo Hospital, Niigata, Japan, 2.Department of Pediatrics, Niigata University Medical and Dental Hospital, Niigata, Japan, 3.Center for Medical Genetics, Niigata University Medical and Dental Hospital, Niigata, Japan, 4.Department of Genetics, Research Institute of Environmental Medicine, Nagoya University, 5.Department of Human Genetics and Molecular Biology, Nagoya University Graduate School of Medicine)

^○Akinori Yoshino¹, Yumiko Ookubo¹, Tetsuya Fukuoka¹, Tokiko Fukuda^1,2, Tsutomu Ogata^1,2,3 (1.Department of Pediatrics, Shizuoka Saiseikai General Hospital, Shizuoka, Japan, 2.Department of Pediatrics, University of Hamamatsu, Hamamatsu, Japan, 3.Department of Pediatrics, Hamamatsu Medical Center, Hamamatsu, Japan)

^○Sakurako Yamamoto¹, Yuri Uchiyama^2,3, Ikuko Shirai⁴, Akihiko Ishiyama¹, Ryuunosuke Nomura¹, Ko Hirata¹, Hirofumi Kashii¹, Ai Hoshino¹, Mitsumasa Fukuda¹, Naomichi Matsumoto², Satoko Kumada¹ (1.Department of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Fuchu, Japan, 2.Department of Human Genetics, Yokohama City University Graduate School of Medicine, Yokohama, Japan, 3.Department of Rare Disease Genomics, Yokohama City University Hospital, Yokohama, Japan, 4.Department of Neuropediatrics, Shimada Ryoiku Center Hachioji, Hachioji, Japan)

^○Yosuke Hosokawa¹, Tsu Yoshimura¹, Shunsuke Oogaya¹, Keitarou Yamada¹, Koichi Maruyama¹, Kiyokuni Miura¹, Hirotomo Saizu² (1.Department of Pediatric neurology, Aichi Developmental Disability Center, Kasugai, Japan, 2.Department Medical Biochemistry, Hamamatsu University School of Medicine, Hamamatsu, Japan)

^○Satomi Okano^1,2, Kayano Kimura², Ikue Fukuda², Aya Tokumitsu³, Akie Miyamoto², Hajime Tanaka² (1.Department of Pediatrics, Sapporo Tokushukai Hospital, Sapporo, Japan, 2.Department of Pediatrics, Asahikawa habilitation Center for Children, Asahikawa, Japan, 3.Department of Pediatrics, Hokkaido Ryoikuen, Asahikawa, Japan)

^○Masafumi Sanefuji¹, Takuji Nakamura¹, Naoya Higuchi¹, Akihiko Asahina², Muneaki Matsuo¹ (1.Department of Pediatrics, Faculty of Medicine, Saga University, 2.Department of Dermatology, The Jikei University School of Medicine)

^○Tomofumi Otomo^1,2, Ikegami Mariko^1,3, Kaiga Chinami¹, Sugiyama Nobuyoshi^2,4 (1.Department of Pediatrics, University of Tokai, Hachioji, Japan, 2.Department of Pediatrics, University of Tokai, Isehara, Japan, 3.Kokoko Children Clinic, Atsugi, Japan, 4.Kanagawa Prefecture Koseiren Isehara Collaborative Hospital, Isehara, Japan)

^○Wakana Furushima, Ito Masahiro (Department of Pediatrics, Tokyo Metropolitan Fuchu Medical Center for the Disabled, Tokyo, Japan)

^○Kei Yamada¹, Hitomi Fujii¹, Eijyun Seki¹, Masaki Miura¹, Moemi Houjo¹, Yu Kobayashi¹, Akiyoshi Kakita², Mitsuko Nakashima³, Hirotomo Saitsu³, Masafumi Fukuda⁴, Makoto Oishi⁵, Jun Tohyama¹ (1.Department of Child Neurology, National Hospital Organization Nishiniigata Chuo Hospital, Niigata, Japan, 2.Department of Pathology, Brain Research Institute, University of Niigata, Niigata, Japan, 3.Biochemistry Department, Hamamatsu University School of Medicine, Hamamatsu, Japan, 4.Department of Neurosurgery, National Hospital Organization Nishiniigata C huo Hospital, Niigata, Japan, 5.Department of Neurosurgery, Brain Research Institute, University of Niigata, Niigata, Japan)

^○Konomi Shimoda^1,2, Hiroshi Terashima¹, Yu Kakimoto¹, Shunpei Uchino¹, Kei Murayama³ (1.Department of Pediatrics, University of Tokyo,Tokyo,Japan, 2.Department of Pediatrics, National Rehabilitation Center for Children with Disabilities, Tokyo, Japan, 3.Diagnostics and Therapeutics of Intractable Disease, Intractable Disease Research Center,Juntendo University Faculty of Medicine)

^○Naoko Shiba^1,2, Kyoko Takano^3,4, Hideko Nakajima⁵, Makoto Nisioka¹, Manami Yabe¹, Tetsuhiro Fukuyama¹ (1.Department of Pediatrics, Shinshu University, Matsumoto, Japan, 2.Regenerative Science and Medicine, Shinshu University, Matsumoto, Japan, 3.Center for Medical Genetics, Shinshu University Hospital, Matsumoto, Japan, 4.Department of Medical Genetics, Shinshu University, Matsumoto, Japan, 5.Pediatrics, Inariyama medical center)

^○Yukie Yasunaga¹, Nakao Taisuke¹, Ogata Reina¹, Watanabe Kyouko¹, Taketani Takeshi² (1.Department of Pediatrics,Kokura Medical Center,Fukuoka,Japan, 2.Department of Pediatrics,University of Shimane,Shimane,Japan)

^○Yukio Sawaishi, Tomoko Sakamoto, Miyuki Toyono, Tamami Yano (Akita Prefectural Center on development and disability)

^○Michi Takahashi, Yukiko Nakamura, Masaya Kubota (Department of Pediatrics, Shimada Ryoiku Medical Center for Challenged Children, Tokyo, Japan)

^○Tomomi Nakamura¹, Takahiro Yonekawa¹, Yosuke Nishio^2,3,4, Hideki Muramatsu², Ogi Tomoo^3,4, Katsumi Sugiura⁵, Hidemi Toyoda¹, Masahiro Hirayama¹ (1.Department of Pediatrics, Mie University Hospital, Mie, Japan, 2.Department of Pediatrics, Graduate School of Medical and Dental Sciences, Nagoya University, Aichi, Japan, 3.Department of Genetics, Research Institute of Environmental Medicine, Nagoya University, Aichi, Japan, 4.Department of Human Genetics and Molecular Biology, Nagoya University Graduate School of Medicine, Aichi, Japan, 5.Department of Pediatrics, Matsusaka Chuo General Hospital, Mie, Japan)

^○Naoya Higuchi¹, Takuji Nakamura¹, Masafumi Sanefuji¹, Tomoko Yamamoto², Hidenobu Soejima³, Toshiyuki Yamamoto⁴, Muneaki Matsuo¹ (1.Department of Pediatrics,University of Saga,Saga,Japan, 2.Department of Obstetrics and gynecology,University of Saga,Saga,Japan, 3.Division of Molecular Genetics and Epigenetics, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Saga,Japan, 4.Institute of Medical Genetics, Tokyo Women's Medical University, Tokyo, Japan.)

^○Kaori Miyana^1,2, Kumiko Yanagi³, Tadashi Kaname³, Yoshihisa Oishi¹ (1.Department of Pediatrics, Japanese red cross medical center, Tokyo, Japan, 2.Higashikoganei pediatric neurology and neurology clinic, 3.Department of Genome Medicine, National Center for Child Health and Development, Tokyo, Japan)

^○Ikushi Shimomura¹, Shinsuke Maruyama¹, Aika Matsunaga¹, Toshiro Ikeda², Yasuhiro Okamoto¹ (1.Department of Pediatrics, University of Kagoshima, Kagoshima city, Japan, 2.Room of genetic counseling, University of Kagoshima, Kagoshima city, Japan)

^○Yusei Baba, Chihiro Yonee, Kazuyuki Yotsumata (Department of Pediatrics, National Hospital Organization Minamikyushu hospital, Kagoshima, Japan)

^○Yasuhiro Kimoto¹, Kotaro Kojima¹, Norihiko Mori¹, Kozue Mori¹, Kennichi Maeda¹, Noriko Hidaka¹, Toshio Ikeda², Hiroshi Moritake¹ (1.The Department of Pediatrics, School of Medicine, University of Miyazaki, Miyazaki, Japan, 2.Matsuoka Pediatric Clinic, Ikeda Child Neurology Clinic, Miyazaki, Japan)

^○Hiroko Shimbo^1,2, Shinobu Hirai¹, Haruo Okado¹ (1.Brain Metabolic Regulation Group, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan, 2.Clinical Research Institute, Kanagawa Children's Medical Center, Kanagawa, Japan)