^○Eri Sakamoto¹, Shino Shimada^1,2, Kaito Yamaguchi², Katsumi Imai², Hidetaka Eguchi³, Toshiaki Shimizu¹, Masami Arai⁴ (1.Department of Pediatrics,University of juntendo, Tokyo, Japan, 2.Department of pediatrics, National Epilepsy Center NHO Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan, 3.Intectable disease reseach senter, University of juntendo, Tokyo, Japan, 4.Department of clinical genetics, University of juntendo, Tokyo, Japan)

^○Hiroshi Terashima^1,2, Nagahisa Takahashi², Konomi Shimoda², Mai Anzai², Eiji Kitazumi², Masashi Mizuguchi² (1.Department of Pediatrics, the University of Tokyo, Tokyo, Japan, 2.Department of Pediatrics, National Rehabilitation Center for Children with Disabilities, Tokyo, Japan)

^○Haruka Takami, Shinnosuke Notake, Ken Ito, Satoru Ikemoto, Norimichi Higurashi (Department of Pediatrics, the Jikei University School of Medicine, Tokyo, Japan)

^○Yuzuka Miyoshi¹, Satoru Sakuma¹, Masakatsu Hagiwara¹, Mayumi Morioka¹, Shuhei Dohi¹, Taeka Hattori¹, Miho Nonomura¹, Emi Tanaka¹, Satoshi Onishi¹, Haruka Bamba², Junko Hotta², Toshiyuki Seto², Takashi Hamazaki¹ (1.Department of Pediatrics, Osaka Metropolitan University, Osaka, Japan, 2.Department of Clinical Genetics, Osaka Metropolitan University, Osaka, Japan)

^○Tomoi Furukawa¹, Satoshi Kajimoto², Yuki Hyodo¹, Toru Takaori¹, Akira Kumakura¹, Taisei Kayaki², Naoko Yano², Takeshi Yoshida², Chunhua Zhang³, Mitsutaka Shiota¹ (1.Medical Research Institute KITANO HOSPITAL, PIIF Tazuke-kofukai, Osaka, Japan, 2.Department of Pediatrics, University of Kyoto, Kyoto, Japan, 3.MILS International, Yokohama, Japan)

^○Hiromi Teranishi^1,2, Satomi Ohtamki^1,2, Kaori Sassa^1,2, Hiroshi Matsumoto^1,2, Hideo Yamanoushi^1,2 (1.Department of Pediatrics, Saitama Medical University Hospital, Saitama, Japan, 2.Epilepsy Center, Saitama Medical University Hospital, Saitama, Japan)

^○Saki Uneoka¹, Yusuke Goto¹, Naoya Saijo¹, Yusuke Takezawa¹, Yurika Uematsu¹, Mitsugu Uematsu¹, Maya Asami², Kanako Mizuma², Sachiko Tanifuji², Manami Akasaka², Jun Takayama³, Gen Tamiya³, Shigeo Kure³, Atsuo Kikuchi^1,3 (1.Department of Pediatrics, University of Tohoku, Sendai, Japan, 2.Department of Pediatrics, Iwate Medical University Hospital, Morioka, Iwate, 3.Tohoku University Graduate School of Medicine, Sendai, Japan)

^○Yu Katata^1,3, Yukimune Okubo², Haruhiko Nakamura³, Naoya Saijyo³, Jun Takayama^4,5,6, Shigeo Kure^1,3,4, Gen Tamiya^4,5,6, Atsuo Kikuch^3,4 (1.Department of Pediatric Neurology, Miyagi Children's Hospital, Sendai, Japan, 2.Department of Pediatrics, Hachinohe City Hospital, Aomori, Japan, 3.Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan, 4.Department of Rare Disease Genomics, Tohoku University Graduate School of Medicine, Sendai, Japan, 5.Department of AI and Innovative Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan, 6.Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan)

^○Yukimune Okubo¹, Kunihiro Sasaki¹, Hinano Yaginuma¹, Hikari Azumaya¹, Yuka Takahashi¹, Arata Sashinami¹, Yuya Ito¹, Manabu Kinjo¹, Yuu Katata², Atsuo Kikuchi² (1.Department of Pediatrics, Hachinohe city hospital, Aomori, Japan, 2.Department of Pediatrics, Tohoku university, Sendai, Miyagi, Japan)

^○Hiromitsu Toshikawa^1,2, Nobusuke Kimura³, Takeo Kato¹, Mitsuhiro Miyashita⁴, Tokito Yamaguchi⁴, Katsumi Imai⁴, Fuyuki Miya⁵, Mitsuhiro Kato⁶, Yoshihisa Higuchi² (1.Department of Pediatrics, Shiga Medical Center for Children, Moriyama, Shiga, 2.Department of Pediatrics, Japanese Red Cross Otsu Hospital, Otsu, Shiga, 3.Department of Pediatrics, Naniwa-Ikuno Hospital, Osaka, Osaka, 4.Department of Epilepsy, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Shizuoka, 5.Center for Medical Genetics, Keio University School of Medicine, Shinjuku, Tokyo, 6.Department of Pediatrics, SHOWA University School of Medicine, Shinagawa, Tokyo)

^○Moriei Shibuya^1,2, Haruhiko Nakamura^1,5, Naoya Saijyo¹, Saki Uneoka¹, Yuusuke Takezawa¹, Yoshitugu Oikawa¹, Yurika Uematsu¹, Mitsugu Uematsu¹, Jyun Takayama^3,4, Shigeo Kure^3,5, Gen Tamiya^3,4, Atsuo Kikuchi^1,3 (1.Department of Pediatrics, University of Tohoku, Sendai, Japan, 2.Yamagata prefectural central hospital, Yamagata, Japan., 3.Department of Genome Analysis for Rare and Intractable Diseases,University of Tohoku,Sendai,Japan, 4.RIKEN Center for Advanced Intelligence Project Statistical Genetics Team,Tokyo,Japan, 5.Miyagi prefectural children hospital)

^○Kenichi Maeda¹, Kozue Mori¹, Noriko Hidaka¹, Yasuhiro Kimoto¹, Toshio Ikeda², Fuyuki Miya³, Mitsuhiro Kato⁴, Hiroshi Moritake¹ (1.Department of Pediatrics, University of Miyazaki, Miyazaki, Japan, 2.Ikeda pediatric neurology clinic, Miyazaki, Japan, 3.Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan, 4.Department of Pediatrics, Showa University School of Medicine, Tokyo, Japan)

^○Eijun Seki¹, Akiko Hiraiwa^1,2, Hitomi Fujii¹, Kei Yamada¹, Masaki Miura¹, Moemi Hojo¹, Yu Kobayashi¹, Jun Tohyama¹ (1.Department of Pediatrics, Nishi Niigata central hospital, Niigata, Japan, 2.Department of Pediatrics, University of Toyama, Toyama, Japan)

^○Kanako Maizuru¹, Ayuko Usami¹, Taisei Kayaki², Naoko Yano², Takeshi Yoshida² (1.Tenri Hospital, 2.Kyoto University Hospital)

^○Naohiro Yamamoto^1,2, Ichiro Kuki², Shin Okazaki^2,3, Masataka Fukuoka², Yayoi Shide¹, Sayaka Yoshida¹ (1.Division of pediatrics, Nara prefecture General Medical Center, Nara, Japan, 2.Epilepsy center of Child and Adolescent, Division of pediatric Neurology, Osaka City General Hospital, Osaka, Japan, 3.Division of logopedics, Osaka City General Hospital, Osaka, Japan)

^○Tomoko Uchida¹, Tadashi Shiohama¹, Kazuyuki Meguro^2,3, Shoko Yoshii¹, Chihiro Saito¹, Sho Hagiwara¹, Tomohiko Ichikawa³, Hiromichi Hamada¹ (1.Department of Pediatrics, Graduate School of Medicine, Chiba University, 2.Department of Allergy and Clinical Immunology, Graduate School of Medicine, Chiba University, 3.Department of Clinical genetics, Chiba University hospital, Chiba, Japan)

^○Ruby Kuroiwa¹, Naoko Asakawa¹, Ayumi Fujita¹, Yayoi Kojima¹, Eiji Nakagawa^1,2 (1.Dravet Syndrome JP, Tokyo, Japan, 2.National Center of Neurology and Psychiatry, Tokyo)

^○Ryo Fujimoto¹, Hiromi Aoyama¹, Risa Kawaguchi¹, Taku Omata² (1.Division of Child Neurology, Chiba Children's Hospital, Chiba, Japan, 2.Division of Child Neurology, Tokyo Women's Medical University Yachiyo Medical Center, Chiba, Japan)

^○Genichi Uetsuki, Yumi Dohi (Department of Pediatrics, Shikoku Medical Center for Children and Adults, Kagawa, Japan)

^○Mitsuhiro Matsuo, Takuya Hayashida, Kaoru Moriyama, Mio Yamashita, Daishi Inoue (Nagasaki Prefectural Center of Medicine and Welfare for Children,Nagasaki,Japan)

^○Chihiro Yonee, Yusei Baba, Kazuyuki Yotsumata (Pediatrics, Minamikyusyu Hospital, Kagoshima, Japan)

^○Masahiro Umeda¹, Tohru Okanishi¹, Satoru Kobayashi², Shinji Itamura³, Yoshimichi Hirayama⁴, Yuto Arai¹, Kento Ohta¹, Yoshihiro Maegaki¹ (1.Division of Child Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Yonago, Japan, 2.Nagoya City West Medical Center, Nagoya, Japan, 3.Hiroshima City Funairi Citizens Hospital, Hiroshima, Japan, 4.Naha City Hospital, Naha, Japan)

^○Kentaro Okamoto¹, Hisamichi Tauchi², Mitsumasa Fukuda³ (1.Pediatrics, Ehime Prefectural Imabari Hospital, 2.Department of Pediatrics, Ehime University Graduate School of Medicine, Toon, Ehime, Japan, 3.Department of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Fuchu, Tokyo, Japan)

^○Satoru Ochiai, Hideki Hoshino, MIzuho Niido, Hideaki Mashimo, Masakazu Mimaki (Department of Pediatrics, Teikyo University, Tokyo, Japan)

^○Ayumi Horiguchi¹, Kaoru Kitamura¹, Yuta Asakura¹, Kiwako Tsukita¹, Kohei Nagai¹, Yoshitaka Mizobe¹, Karin Kojima¹, Yukifumi Monden¹, Kazuhiro Muramatsu¹, Naomichi Matsumoto¹, Hirotomo Saitsu^2,3, Hitoshi Osaka¹ (1.Tochigi Children's Medical Center, Jichi Medical University Hospital, Tochigi, Japan, 2.Department of Genetics, Yokohama City University, 3.Department of Medical Chemistry, Hamamatsu University School of Medicine)

^○Ayuko Igarashi^1,2, Mitsuru Ikeno¹, Shinpei Abe¹, Toshiaki Shimizu¹ (1.Department of Pediatrics, University of Juntendo, Tokyo, Japan, 2.Department of Pediatrics, Tokyo Rinkai Hospital, Tokyo, Japan)

^○Mayuka Sato¹, Manami Yabe¹, Makoto Nishioka¹, Kyoko Takano², Tetsuhiro Fukuyama¹ (1.Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, 2.Center of Medical Genetics, Shinshu University School of Medicine, Matsumoto)

^○Masahiro Ishii (Department of Pediatrics, Kitakyushu general hospital, Kitakyushu, Japan)

^○Luna Takaichi, Rie Miyata (Tokyo/Japan)

^○Hideo Enoki^1,2, Keisuke Hatano¹, Keishiro Sato¹, Ayataka Fujimoto¹ (1.Comprehensive Epilepsy Center, Seirei Hamamatsu General Hospital, Hamamatsu, Japan, 2.Department of Pediatrics, Kawasaki Medical School, Kurashiki, Japan)

^○Hideaki Kanemura¹, Shohei Nishimoto², Miku Nakai², Taisei Tsuruda², Naoki Akamatsu³ (1.Department of Pediatrics, Toho University Sakura Medical Center, Chiba, Japan, 2.Medical Headquarters, Eisai Co., Ltd., Tokyo, Japan, 3.Neurology, International University of Health and Welfare, Chiba Japan)

^○Junichi Onuma¹, Shinichiro Takeuchi¹, Kenji Takazawa², Hikoe Suzuki³, Kikuo Tsukahara¹ (1.Aculys Pharma Inc., Tokyo, Japan, 2.Shinanozaka Clinic, Tokyo, Japan, 3.CMIC HOLDINGS Co., Ltd., Tokyo, Japan)

^○Taichi Imaizumi^1,3, Etsurou Nakanishi², Maiko Nakashima³, Shoutarou Kaku³, Hisako Yamamoto³, Shuji Hashimoto³, Natsuko Arai³, Noriko Udagawa³, Toshiyuki Iwasaki^1,3, Kenji Sugai⁴, Hitoshi Yamamoto³, Yusaku Miyamoto³, Naoki Shimizu³ (1.Department of pediatrics, Kawasaki Municipal Tama Hospital, 2.Department of Neurology Kyoto University Graduate School of Medicine, 3.Department of pediatrics, St.Marianna University School of Medicine, 4.Soreiyu Kawasaki)

^○Ryuta Ishii, Daisuke Yamashita, Kouhei Goto, Koutaro Yuge, Takayoshi Koike, Munetsugu Hara, Yushiro Yamashita (Department of pediatrics and Child Health, Kurume University School of Medicine)

^○Takamasa Kishi (Department of Pediatrics, Araki Neurosurgical Hospital, Hiroshima City, Japan)

^○Mika Nakazawa^1,2, Shinpei Abe², Mitsuru Ikeno², Ayuko Igarashi², Toshiaki Shimizu² (1.Department of Pediatrics, Sanikukai Hospital, Tokyo, Japan, 2.Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan)

^○Yusuke Watanabe, Shinichiro Morichi, Haruka Nakazawa, Rie Shimizu, Tomoko Takamatsu, Mika Takeshita, Natsumi Morishita, Yu Ishida, Shingo Oana, Gaku Yamanaka (Department of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan)

^○Kaoru Amemiya, Akiko Miyata (Department of home medical care,Saiwaikodomo clinic,Tokyo,Japan)

^○Akihiro Iguchi, Tomona Yabe, Mitsuhiro Miyashita, Satoshi Mizutani, Tokito Yamaguchi, Hideyuki Ootani, Katsumi Imai (National Epilepsy Center, NHO Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama Aoi-ku Shizuoka 42-8688, Japan)

^○Tomohiro Fujii, Hirowo Omatsu, Ayami Ozaki, Takako Matsumoto, Yuko Fukumura, Fumiyo Hirabayashi, Maiko Kita, Makiko Kurosawa, Naoko Miura, Saoko Takeshita, Atsuo Nezu (Department of Neuropediatrics, Yokohama Medical and Welfare Centre, Konan, Yokohama, Japan)

^○Azusa Ikeda¹, Shotaro Morikawa¹, Tamaki Ikegawa¹, Kana Osada¹, Yu Tsuyusaki¹, Megumi Tsuji¹, Hiroyuki Nagafuchi², Kenji Kurosawa³, Tomohide Goto¹ (1.Department of Neurology, Kanagawa Children's Medical Center, Yokohama, Japan, 2.Department of Pediatric Intensive Care Medicine, Kanagawa Children's Medical Center, Yokohama, Japan, 3.Division of Medical Genetics, Kanagawa Children's Medical Center, Yokohama, Japan)

^○Akira Akutsu, Yuji Fujita, Hiroaki Hitomi, Fumitaka Takayanagi, Yuusuke Andou, George Imataka, Shigemi Yoshihara (Department of Pediatrics, Dokkyo Medical University, Tochigi, Japan)

^○Harumi Yoshinaga, Fumika Endo, Michiko Inoue (National Hospital Organization Minami-Okayama Medical Hospital,Tukubo-gun,Japan)

^○Takahiro Motoki, Chisato Yajima, Toshihiro Jogamoto, Mariko Eguchi (Department of Pediatrics, Ehime University Graduate School of Medicine, Toon, Ehime, Japan)

^○Takashi Saito¹, Go Taniguchi², Eiji Nakagawa² (1.Department of Child Neurology, National Center of Neurology and Psychiatry, Kodaira, Japan, 2.Department of Epileptology, National Center of Neurology and Psychiatry, Kodaira, Japan)

^○Gen Furukawa^1,2, Hidetaka Nakai², Naoko Ishihara¹ (1.Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Japan, 2.Department of Pediatrics, Toyokawa City Hospital)

^○Hitomi Fujii, Eijun Seki, Kei Yamada, Moemi Hojo, Masaki Miura, Yu Kobayashi, Jun Tohyama (Department of Child Neurology, National Hospital Organization Nishiniigata Chuo Hospital, Niigata, Japan)

^○Kei Tamaru^1,2, Sayaka Ishii², Kakuro Aoyagi¹, Takeshi Inukai¹, Yoshimi Kaga¹ (1.Departmemt of Pediatrics,University of Yamanashi,chuo city,Japan, 2.Department of Pediatrics,National Hospital Orgnization Kofu National Hospital)

^○Masahiro Ito, Naoyuki Tanuma, Wakana Furushima, Ayaka Koide, Nao Saito (Department of Pediatrics, Tokyo Metropolitan Fuchu Rehabilitation Center)

^○Takayoshi Koike, Daisuke Yamashita, Teiko Yoshiduka, Ryuta Ishii, Kotaro Yuge, Munetsugu Hara, Yushiro Yamashita (The department of pediatrics and child health Kurume university school of medicine, Fukuoka, Japan,)

^○Shin Okazaki¹, Takuya Kumagai², Shinichi Nishiuma², Katsuhiko Iwasaki³, Kazuaki Yamamoto³, Kinya Kokubo^3,4, Hiroomi Hayashi⁵, Eiji Nakagawa⁶ (1.Osaka City General Hospital, Osaka, Japan, 2.Aculys Pharma Inc., Tokyo, Japan, 3.Healthcare Consulting Inc., Tokyo, Japan, 4.Nishogakusha-university, Tokyo, Japan, 5.KNOCK ON THE DOOR Inc., Tokyo, Japan, 6.National Center of Neurology and Psychiatry, Tokyo, Japan)

^○Shin Okazaki¹, Takuya Kumagai², Shinichi Nishiuma², Katsuhiko Iwasaki³, Kazuaki Yamamoto³, Kinya Kokubo^3,4, Hiroomi Hayashi⁵, Eiji Nakagawa⁶ (1.Osaka City General Hospital, Osaka, Japan, 2.Aculys Pharma Inc., Tokyo, Japan, 3.Healthcare Consulting Inc., Tokyo, Japan, 4.Nishogakusha-university, Tokyo, Japan, 5.KNOCK ON THE DOOR Inc., Tokyo, Japan, 6.National Center of Neurology and Psychiatry, Tokyo, Japan)

^○Hiroyasu Nakagawa¹, Mondo Kuroda² (1.Department of Pediatrics, Asanogawa Gereral Hospital, Kanazawa, Japan, 2.Department of Pediatrics, Kanazawa University, Kanazawa, Japan)

^○Masayuki Heishi^1,2, Koichi Kawata¹, Chihiro Takayama^1,2, Hiroomi Hayashi², Shin Okazaki³ (1.General Incorporated Association SAChi Project, Osaka, Japan, 2.KNOCK ON THE DOOR Inc, Tokyo, Japan, 3.Osaka City General Hospital, Osaka, Japan)

^○Hiroyuki Yamada, Kazuki Suemune, Hiromi Fujibayashi, Masaaki Ueda, Toshinori Minato (Department of Pediatrics, Toyooka Public Hospital, Toyooka, Japan)

^○Takuya hayashida, Kaoru Moriyama, Daishi Inoue, Mio Yamashita, Mitsuhiro Matsuo (Department of pediatrics, nagasaki prefectural center of medical and welfare for children, Nagasaki, japan)

^○Fumikazu Sano^1,2,3, Eiji Shigetomi^1,3, Schuichi Koizumi^1,3, Takeshi Inukai², Yoshimi Kaga² (1.Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan, 2.Department of Pediatrics, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan, 3.Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan)

^○Hiroki Hoshino^1,2,3, Fumikazu Sano^1,2,4, Eiji Shigetomi^1,2, Hideyuki Takeuchi^5,6,7, Hideaki Kanemura³, Schuichi Koizumi^1,2 (1.Department of Neuropharmacology, Interdisciplinary of Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan, 2.Yamanashi GLIA center, 3.Department of Pediatrics, Faculty of Medicine, University of Toho, Tokyo, Japan, 4.Department of Pediatrics, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan, 5.Department of Neurology, Yokohama City University Graduate School of Medicine, Kanagawa, Japan, 6.Department of Neurology, Faculty of Medicine, International University of Health and Walfare, 7.Center of intractable neurological disease and dementia, International University of Health and Walfare Atami Hospital)