Symposium 8
The impact of early life adversity on brain and behavior

[IS8-2] Early social isolation stress potentiates heroin seeking by aggravating the dysfunction of prelimbic cortex to ventral tegmental area projection

*Zijun Wang¹, Yunwanbin Wang¹, Shuwen Yue¹, Fengwei Yang^2,3, Mcdonald J Stuart ¹ (1. University of Kansas, 2. University of Kansas Medical Center, 3. The Kansas Department of Health and Environment )

Keywords:early life stress, prefrontal cortex, opioid addiction, TRAP, ventral tegmental area