基礎臨床融合研究

[JP10-5] Effect of lemborexant on pharmacokinetics of clozapine: A potential drug–drug interaction mediated by time-dependent inhibition of CYP3A4

*Kenya Watanabe¹, shingen Misaka², Keiko Kanno-Nozaki³, Sae Endo¹, Yuhei Suzuki³, Yuri Koboyashi³, Shoichiro Hirata³, Mizue Ichinose³, Sho Horikoshi⁴, Takahiro Suto¹, Junko Kuroda¹, itaru Miura³ (1. Department of Pharmacy, Fukushima Medical University Hospital, 2. Department of Bioregulation and Pharmacological Medicine, School of Medicine, Fukushima Medical University School of Medicine, 3. Department of Neuropsychiatry, School of Medicine, Fukushima Medical University School of Medicine, 4. HORIKOSHI psychosomatic clinic)