Anxiety Disorders

[P040] IGFBP2 attenuates restrain stress-induced anxiety-like behavior via modulating the myelination and synaptic plasticity in the medial prefrontal cortex

*Ying-Dan Zhang¹, Dong-Dong Shi^1,2, Sen Zhang², Zhen Wang^1,2,3 (1. Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China., 2. Shanghai Key Laboratory of Psychotic disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China., 3. Institute of Psychological and Behavioral Science, Shanghai Jiao Tong University, Shanghai, China)

Keywords:IGFBP2, mPFC, Restrain stress, Anxiety disorder, Myelination