Bipolar Disorders (1)

[P059] Repurposing Candesartan, the antihypertensive drug, for treatment of bipolar disorder

*Johnny (Chun Hui) Park¹, Melanie Ashton¹, Judy Hope², Chee Ng³, Malcolm Hopwood⁴, Jon-Paul Khoo^1,5, Gin Malhi^6,7, Brisa Fernandes⁸, Stella May Gwini⁹, John Amerena¹⁰, Trisha Suppes^11,12, Mary Lou Chatterton², Lana Williams¹, Adam Walker¹, Alyna Turner¹, Andre Carvalho¹, Andrew Nierenberg¹³, Emily Moriaty¹, Lars Kessing^14,15, Mohammedreza Mohebbi¹⁶, Seetal Dodd¹, Steven Moylan¹, Jose Segal², John Tiller⁴, Joel King³, Jeremy Couper², Jee Hyun Kim^1,17, Olivia Dean^1,17, Michael Berk^1,17,18,19 (1. Deakin University, IMPACT - the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia , 2. Monash University, Eastern Health and Centre of Mental Health Education and Research at Delmont Private Hospital, Melbourne, VIC, Australia, 3. The Melbourne Clinic, Department of Psychiatry, University of Melbourne, 130 Church St, Richmond, Australia, 4. Department of Psychiatry, University of Melbourne, Professorial Psychiatry Unit, Albert Road Clinic, Melbourne, Australia, 5. Faculty of Medicine, The University of Queensland, Brisbane QLD, Australia, 6. Discipline of Psychiatry, Sydney Medical School, University of Sydney, Sydney, Australia, 7. CADE Clinic, Department of Psychiatry, Royal North Shore Hospital, St. Leonards, Australia, 8. Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA, 9. University Hospital Geelong, Department of Research, Geelong, Victoria, Australia, 10. University Hospital Geelong, Geelong, VIC, 11. Bipolar and Depression Research Program, VA Palo Alto Health Care System, 3801 Miranda Avenue (151T), Palo Alto, CA, 94304, USA, 12. Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA, 94305, USA, 13. The Dauten Family Center for Bipolar Treatment Innovation, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA, 14. Copenhagen Affective Disorders Research Centre (CADIC), Psychiatric Center Copenhagen, Rigshospitalet, and Faculty of Health and Medical Sciences, 15. University of Copenhagen, 6243, Rigshospitalet. Blegdamsvej 9, 2100 Copenhagen, Denmark, 16. Biostatistics Unit, Faculty of Health, Deakin University, Burwood, Australia, 17. Florey Institute for Neuroscience and Mental Health, University of Melbourne, Parkville, Australia, 18. Department of Psychiatry, University of Melbourne, Parkville, Australia, 19. Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia)

Keywords:Bipolar Depression, Clinical Trial, Angiotensin, Unipolar Depression