Sleep Disorders

[P297] Inhibition of histamine metabolizing enzyme in the brain reduces cataplexy in narcolepsy model mice

*Takeo Yoshikawa¹, Birkan Girgin¹, Anne Bernadette Agu¹, Tadaho Nakamura², Kazuhiko Yanai⁴, Takatoshi Mochizuki³, Shota Nagasawa⁵, Yoshiharu Iwabuchi⁵, Fumito Naganuma¹ (1. Hokkaido University, 2. Tohoku Medical and Pharmaceutical University, 3. University of Tsukuba, 4. Sendai Shirayuri Women's College, 5. Tohoku University)

Keywords:histamine, narcolepsy, cataplexy, drug development