Autism

[P314] POGZ mutant mouse model of autism spectrum disorder shows abnormal neural activity in the anterior cingulate cortex during social behavior.

*Kohei Kitagawa¹, Tomoya Takemoto¹, Kaoru Seiriki¹, Atsushi Kasai^1,2, Hitoshi Hashimoto^1,3,4,5,6, Takanobu Nakazawa⁷ (1. Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan, 2. Systems Brain Science Project, Drug Innovation Center, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan, 3. United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University and University of Fukui, Japan, 4. Division of Bioscience, Institute for Datability Science, Osaka University, Osaka, Japan, 5. Transdimensional Life Imaging Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Osaka, Japan, 6. Department of Molecular Pharmaceutical Science, Graduate School of Medicine, Osaka University, Osaka, Japan, 7. Department of Bioscience, Faculty of Bioscience, Tokyo University of Agriculture, Tokyo, Japan)

Keywords:Autism, Animal models, Anterior cingulate cortex