Dementia 2 - Preclinical and others

[P381] Overexpression of Shati/Nat8l in the hippocampus ameliorates cognitive dysfunction in model mice with Alzheimer’s disease

*Naotaka Izuo¹, Daiki Ikejima¹, Kakeru Chino¹, Takashi Asano¹, Tomoharu Kuboyama², Chihiro Tohda³, Shin-Ichi Muramatsu^4,5, Atsumi Nitta¹ (1. Department of Pharmaceutical and Neuropharmacological Therapy, Faculty of Pharmaceutical Sciences, Graduate School of Medical and Pharmaceutical Sciences, University of Toyama, 2. Laboratory of Pharmacognosy, Daiichi University of Pharmacy, 3. Section of Neuromedical Science, Institute of Natural Medicine, University of Toyama, 4. Division of Neurological Gene Therapy, Open Innovation Center, Jichi Medical University, 5. Center for Gene and Cell Therapy, The Institute of Medical Science, The University of Tokyo)

Keywords:Shati/Nat8l, Alzheimer's disease, Cognitive dysfunction