Dementia 2 - Preclinical and others

[P387] Intra-hippocampal injection of alpha-synuclein pre-formed fibrils triggers cognitive defect and changes transcriptome profiles.

*Yu Ting Huang¹, Jin Chung Chen¹, Yu Ying Li² (1. Graduate Institute of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan, 2. Department and Graduate Institute of Pharmacology, National Taiwan University, Taipei, Taiwan )

Keywords:Parkinson's disease, dementia, α-synuclein, synucleinopathy, TGFβ