Depression 6 - Translational

[P457] Utilizing Structural Equation Modeling to Analyze Polygenic Risk and Environmental Influences on Late-Life Depression

*Samar Salah Mohamedahmed Elsheikh¹, Victoria Marshe², James Kennedy^1,3, Guillaume Paré⁴, Corinne Fischer⁵, Daniel Felsky^1,3, Daniel Mueller^1,3 (1. Center for Addiction and Mental Health, Toronto, ON, Canada, 2. Colombia University, New York, NY, USA, 3. University of Toronto, Toronto, ON, Canada, 4. McMaster University, Hamilton, ON, Canada, 5. St. Michael's Hospital, Toronto, ON, Canada)

Keywords:Late-life Depression, Antidepressant Response, Polygenic Risk Score