Medical care/Health care/Biotechnology

[1PC-111] Design, Synthesis and RNase H activity of Hemi-Gapmer Type Peptide Ribonucleic Acid (PRNA)-DNA chimeras for the RNase H mediated catalytic oligonucleotide therapeutics

04.ATP Poster

○INAGAKI, Masahito; UNABARA, Daisuke; UEMATSU, Ryohei; ARAKI, Yasuyuki; ISHIBASHI, Satoru; YOKOTA, Takanori; WADA, Takehiko (IMRAM, Tohoku Univ.; Neuro.,Tokyo Med. and Dental Univ.)

Keywords:Peptide Ribonucleic Acid (PRNA)、Hemi-gapmer type chimeric PRNA-DNA、Ischemia-Selective Oligonucleotide Therapeutics、RNase H mediated catalytic RNA cleavage、Antisense activity