Enantioselective Friedel-Crafts Alkylation Reaction of Indoles with non-activated β-Alkyl-β-Nitrostyrenes Catalyzed by Chiral BINOL Phosphates

○KANEKO

Presentation information

Academic Program (AP)

Organic Chemistry -Reaction and Synthesis- Aliphatic and Alicyclic Compounds

Thu. Mar 22, 2018 1:30 PM - 5:30 PM H4 (1141, Bldg. 11)

3H4-28～3H4-32　MIYAGAWA, Masamichi
3H4-35～3H4-40　ITOH, Toshiyuki
3H4-42～3H4-47　SAITO, Akio
3H4-49～3H4-51　TANIMOTO, Hiroki

3:10 PM - 3:20 PM

[3H4-38] Enantioselective Friedel-Crafts Alkylation Reaction of Indoles with non-activated β-Alkyl-β-Nitrostyrenes Catalyzed by Chiral BINOL Phosphates

01.Oral A

○KANEKO, Mio; IBÁ□EZ SÁNCHEZ, Ignacio; AKIYAMA, Takahiko (Fac. Sci., Gakushuin Univ.)

PC Setting Time : 14:30 - 14:40

Keywords:Friedel-Crafts alkylation reaction、chiral metal BINOL bis(phosphate) complex、Lewis acid catalyst、all-carbon quaternary center、chiral aromatic indole derivatives