Synthesis and biological evaluation of natural product-mimicking 7,6-spirocyclic imine compounds toward a specific inhibitor of neuronal nicotinic acetylcholine receptor

Presentation information

Academic Program (AP)

Chemical Biology

Fri. Mar 23, 2018 9:00 AM - 12:20 PM D3 (933, Bldg. 9)

4D3-01～4D3-05　TAKAHASHI, Daisuke
4D3-08～4D3-12　UCHINOMIYA, Shohei
4D3-15～4D3-19　KUBOTA, Ryou

12:00 PM - 12:20 PM

[4D3-19] Synthesis and biological evaluation of natural product-mimicking 7,6-spirocyclic imine compounds toward a specific inhibitor of neuronal nicotinic acetylcholine receptor

○MINAMINO, Kou; TSUCHIKAWA, Hiroshi; MURATA, Michio; KONOKI, Keiichi (Grad. Sch. Sci., Osaka Univ.)

PC Setting Time : 11:10 - 11:20

Keywords:nicotinic acetylcholine receptor、spirolide、spiroimine、selective synthesis、structure-activity relationship study