Biofunctional Chemistry ; Biotechnology

[4D7-08] Design, Synthesis and RNase H activity of Hemi-Gapmer Type Peptide Ribonucleic Acid (PRNA)-DNA chimeras for the RNase H mediated catalytic oligonucleotide therapeutics

02.Oral B

○INAGAKI, Masahito; UNABARA, Daisuke; UEMATSU, Ryohei; ARAKI, Yasuyuki; ISHIBASHI, Satoru; YOKOTA, Takanori; WADA, Takehiko (IMRAM, Tohoku Univ.; Neuro.,Tokyo Med. and Dental Univ.)

PC Setting Time : 10:00 - 10:10

Keywords:Peptide Ribonucleic Acid (PRNA)、Hemi-gapmer type chimeric PRNA-DNA、Ischemia-Selective Oligonucleotide Therapeutics、RNase H mediated catalytic RNA cleavage、Antisense activity