Session information

Academic Program (AP)

Chemical Biology

Chemical Biology

Sun. Mar 17, 2019 1:30 PM - 4:50 PM F6 (356, Bldg. 3 [5F])

2F6-28～2F6-33　INUKI, Shinsuke
2F6-35～2F6-40　KUBOTA, Ryou
2F6-42～2F6-46　SATO, Shinichi

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1:30 PM - 1:40 PM

[2F6-28] Polymeric ligand-directed chemstry (1) : Labeling reagent design and reactivity evaluation

Oral A

○TAKU, Kanaya; SHOGO, Torigoe; RYOU, Kubota; ITARU, Hamachi (Sch. Eng., Kyoto Univ.; Grad. Sch. Eng., Kyoto Univ.; ERATO, JST)

PC Setting Time : 13:20 - 13:30

1:40 PM - 1:50 PM

[2F6-29] Polymer-tethered Ligand Directed Chemistry(1): Chemical modification of proteins in vivo

Oral A

○TORIOGOE, Shogo; KANAYA, Taku; KUBOTA, Ryou; HAMACHI, Itaru (Sch. Eng., Kyoto Univ.; Grad. Sch. Eng., Kyoto Univ.; ERATO, JST)

PC Setting Time : 13:20 - 13:30

1:50 PM - 2:00 PM

[2F6-30] Analysis of reaction activation mechanism of β-chlorofluoroethylamine (CFE) and its application to protein labeling

Oral A

○SATO, Mami; SHINDO, Naoya; OJIDA, Akio (Grad. Sch. Pharm., Kyushu Univ.)

PC Setting Time : 13:20 - 13:30

2:00 PM - 2:20 PM

[2F6-31] Proximity-dependent labeling on ruthenium photocatalyst-functionalized affinity beads

Oral B

○TSUSHIMA, Michihiko; SATO, Shinichi; NAKAMURA, Hiroyuki (Lab. Chem. Life Sci., Tokyo Tech.; Sch. Life Sci. Tech., Tokyo Tech.)

PC Setting Time : 13:20 - 13:30

2:20 PM - 2:30 PM

[2F6-33] Development of site-selective labeling of antibody using ruthenium photocatalyst-functionalized affinity beads

Oral A

○NAKANE, Keita; TSUSHIMA, Michihiko; SATO, Shinichi; NAKAMURA, Hiroyuki (Lab. Chem. Life Sci., Tokyo Tech.; Sch. Life Sci. Tech., Tokyo Tech.)

PC Setting Time : 13:20 - 13:30

2:40 PM - 2:50 PM

[2F6-35] Design, Synthesis and Biological Evaluation of H₂O₂ Activatable Photosensitizer based on the Aromatic Ring Moiety of Neocarzinostatin Chromophore

Oral A

○KITAMURA, Takashi; SHIROSHITA, Saori; TAKAHASHI, Daisuke; TOSHIMA, Kazunobu (Fac. Sci. Tech., Keio Univ.)

PC Setting Time : 14:30 - 14:40

2:50 PM - 3:00 PM

[2F6-36] Photodegradation of Influenza Virus Hemagglutinin and Inhibitory Activity toward Influenza Virus Infection by Anthraquinone-Sialic Acid Hybrids

Oral A

○HORIKAWA, Ryota; MATSUBARA, Teruhiko; SATO, Toshinori; TAKAHASHI, Daisuke; TOSHIMA, Kazunobu (Fac. Sci. Tech., Keio Univ.)

PC Setting Time : 14:30 - 14:40

3:00 PM - 3:10 PM

[2F6-37] Tryptophan-Linked Homogeneous Antibody-Drug Conjugate

Oral A

○MARUYAMA, Katsuya; ISHIYAMA, Takashi; KAWAMURA, Atsushi; SAIKI, Kuniko; KOBAYASHI, Yuki; SEKI, Yohei; IGUCHI, Keita; MITSUDA, Masaru; OISAKI, Kounosuke; KANAI, Motomu (Grad. Sch. Pharm., The Univ. of Tokyo)

PC Setting Time : 14:30 - 14:40

3:10 PM - 3:20 PM

[2F6-38] Development of dual modified albumin with cyclic RGD peptide and closo-dodecaborates as an active tumor targeting boron agent for neutron capture therapy

Oral A

○KAWAI, Kazuki; SATO, Shinichi; NAKAMURA, Hiroyuki (Lab. Chem. Life Sci., Tokyo Tech.; Sch. Life Sci. Tech., Tokyo Tech.)

PC Setting Time : 14:30 - 14:40

3:20 PM - 3:30 PM

[2F6-39] CDR-selective antibody functionalization using tyrosine chemical labeling

Oral A

○SATO, Shinichi; MATSUMURA, Masaki; NAKAMURA, Hiroyuki (Lab. Chem. Life Sci., Tokyo Tech.)

PC Setting Time : 14:30 - 14:40

3:30 PM - 3:40 PM

[2F6-40] Design, Synthesis and biological evaluation of novel NAMPT inhibitors with dicarborane.

Oral A

○ASAWA, Yasunobu; YOSHIMORI, Atsushi; NAKAMURA, Hiroyuki (Lab. Chem. Life Sci., Tokyo Tech.)

PC Setting Time : 14:30 - 14:40

3:50 PM - 4:00 PM

[2F6-42] Selective Induction of Cancer Cell Death through Complement-Dependent Cytotoxicity by Cell Surface Glycoengineering

Oral A

○YOSHIKAMI, Shingo; SHIMURA, Takumi; TAKAHASHI, Daisuke; TOSHIMA, Kazunobu (Fac. Sci. Tech., Keio Univ.)

PC Setting Time : 15:40 - 15:50

4:00 PM - 4:10 PM

[2F6-43] Fabrication of SN-38 regioisomers drug nanoparticles and evaluation on its hydrolysis susceptibility

Oral A

○TANITA, Keita; KOSEKI, Yoshitaka; KASAI, Hitoshi (IMRAM, Tohoku Univ.)

PC Setting Time : 15:40 - 15:50

4:10 PM - 4:20 PM

[2F6-44] Fabrication and evaluation of cell membrane-coated SN-38 nano-prodrugs

Oral A

○YMAUCHI, Keitaro; KOSEKI, Yoshitaka; KASAI, Hitoshi (IMRAM, Tohoku Univ.)

PC Setting Time : 15:40 - 15:50

4:20 PM - 4:30 PM

[2F6-45] Desilylation reaction catalyzed by trifluoroborate and its application to organocatalyst-conjugated biomolecule

Oral A

○FUJIKI, Katsumasa; TANAKA, Katsunori (Bio. Syn. Chem. Lab., RIKEN CPR; GlycoTargeting Res. Lab., RIKEN BZP)

PC Setting Time : 15:40 - 15:50

4:30 PM - 4:50 PM

[2F6-46] Inhibition of Tumor Metastasis and Proliferation by in vivo Metal Catalyzed Reaction

Oral B

○TSUBOKURA, Kazuki; VONG, Kenward; AHMADI, Peni; NAKAO, Yoichi; TANAKA, Katsunori (RIKEN, CPR Biofunctional Synthetic Chemistry Lab.; Grad. Sch. Advanced Sci. Eng., Waseda Univ.; A. Butlerov Inst. of Chem., Kazan Federal Univ.; RIKEN, BZP GlycoTargeting Research Lab.)

PC Setting Time : 15:40 - 15:50