Biofunctional Chemistry ; Biotechnology

[2G4-08] Improving stability and anticoagulant activity of thrombin binding aptamer by incorporation of 8-trifluoromethyl-2'-deoxyguanosine

Oral B

○BAO, Hongliang; ISHIZUKA, Takumi; XU, Yan (Fac. Med., Univ. of Miyazaki)

PC Setting Time : 10:00 - 10:10

Keywords:Thrombin binding aptamer、G-quadruplex structure、8-trifluoromethyl-2’-deoxyguanosine、anticoagulant activity、thermodynamic stability