Construction of pharmacophore structure of marine natural product containing a spiroimine ring and evaluation of the inhibitory activity against a nicotinic acetylcholine receptor

10:30 AM - 10:40 AM

[4F6-10] Construction of pharmacophore structure of marine natural product containing a spiroimine ring and evaluation of the inhibitory activity against a nicotinic acetylcholine receptor

○MINAMINO, Kou; TSUCHIKAWA, Hiroshi; MURATA, Michio; KONOKI, Keiichi (Sch. Sci., Osaka Univ.)

PC Setting Time : 10:00 - 10:10

Keywords:Nicotinic acetylcholine receptor、Spiroimine、Selective Diels-Alder reaction、Structure-activity relationship、Competitive binding assay

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