Oral

[O25-2] O25-2: CNS and miscellaneous

Mon. Sep 25, 2017 1:30 PM - 2:30 PM Room D (1F)

Chairs: Koichiro Tsuchiya, Japan / Yasuo Takeda, Japan

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[O25-2-1] CYP2C19 polymorphism affects the efficacy but not drowsiness in the low dose clobazam therapy

Sachiyo Hashi¹, Ikuko Yano², Mai Shibata³, Riki Matsumoto⁴, Akio Ikeda⁵, Atsushi Yonezawa⁶, Ryosuke Takahashi⁷, Kazuo Matsubara⁸ (1.Kyoto University Hospital, 2.Kobe University Hospital, 3.Kyoto University, 4.Kyoto University, 5.Kyoto University, 6.Kyoto University, 7.Kyoto University, 8.Kyoto University Hospital)

[O25-2-2] Correlation between serum concentrations of clozapine, N-desmethylclozapine and ABCB1 genotype on neutrophil granulocyte count in schizophrenia patients

Robert Lovsletten Smith¹, Tore Haslemo², Kjersti Bjoentegaard³, Ole Andreassen⁴, Espen Molden⁵ (1.Diakonhjemmet Hospital, 2.Diakonhjemmet Hospital, 3.Diakonhjemmet Hospital, 4.NORMENT K.G. Jebsen Centre for Psychosis Research, 5.Diakonhjemmet Hospital)

[O25-2-3] Quantification and explanation of the pharmacokinetic variability in factor VIII-response in non-severe hemophilia A patients treated with desmopressin

Reinier van Hest¹, Lisette Schutte², Carina Stoof³, Frank Leebeek⁴, Marjon Cnossen⁵, Marieke Kruip⁶, Ron Mathot⁷ (1.Academic Medical Center Amsterdam, 2.Erasmus Medical Center Rotterdam, 3.Erasmus Medical Center Rotterdam, 4.Erasmus Medical Center Rotterdam, 5.Erasmus Medical Center Rotterdam, 6.Erasmus Medical Center Rotterdam, 7.Academic Medical Center Amsterdam)

[O25-2-4] CYP activity in paired human liver and jejunum samples

Veronica Krogstad¹, Alexandra Peric², Ida Robertsen³, Philip Carlo Angeles⁴, Rune Sandbu⁵, Line Kristin Johnson⁶, Joran Hjelmesaeth⁷, Cecilia Karlsson⁸, Shalini Andersson⁹, Anders Asberg¹⁰, Tommy Andersson¹¹, Hege Christensen¹² (1.University of Oslo, 2.AstraZeneca Gothenburg, 3.University of Oslo, 4.The Morbid Obesity Center and Vestfold Hospital Trust, 5.The Morbid Obesity Center and Vestfold Hospital Trust, 6.The Morbid Obesity Center and Vestfold Hospital Trust, 7.The Morbid Obesity Center and Vestfold Hospital Trust, 8.AstraZeneca Gothenburg, 9.AstraZeneca Gothenburg, 10.University of Oslo, 11.AstraZeneca Gothenburg, 12.University of Oslo)