[P26-9-1] Delayed high-dose methotrexate excretion: is there any relationship with proton pump inhibitors in patients with hematological malignancy?

Wei-Jian Ni¹, Tong Tong², Shan-Tang Zhang³, Li-Qin Tang⁴, Ai-Zong Shen⁵ (1.Anhui Provincial Hospital, Anhui Medical University, 2.Anhui Provincial Hospital, Anhui Medical University, 3.Anhui Provincial Hospital, Anhui Medical University, 4.Anhui Provincial Hospital, Anhui Medical University, 5.Anhui Provincial Hospital, Anhui Medical University)

[P26-9-2] Pharmacokinetics of plasma busulfan using isotope dilution mass spectrometry: a pilot study of patients receiving hematopoietic cell transplant in Taiwan

Wei-Chi Ku¹, Li-Hua Fang², Xin-Yi Yang³, Rong-Long Chen⁴, Wen-Hui Ku⁵, Yen-Fu Chen⁶, Erik van Maarseveen⁷ (1.Fu Jen Catholic University, 2.Koo Foundation Sun Yat-Sen Cancer Center, 3.Koo Foundation Sun Yat-Sen Cancer Center, 4.Koo Foundation Sun Yat-Sen Cancer Center, 5.Taipei Institute of Pathology, 6.Fu Jen Catholic University, 7.University Medical Center Utrecht)

[P26-9-3] Dihydromyricetin inhibits human osteosarcoma cells metastasis by suppressing uPA activation through the ERK1/2 signaling pathway

Chia-Hsuan Chou (Chung Shan Medical University)

[P26-9-4] Protodioscin induces mitochondria mediated apoptosis through endoplasmic reticulum stress and reactive oxygen species-dependent pathway in human cervical cancer cells

Chia-Liang Lin¹, Yi-Hsien Hsieh² (1.Chung Shan Medical University, 2.Chung Shan Medical University)

[P26-9-5] Metformin inhibit tumor progression by nickel chloride via p-AKT related autophagy

Yu-Ting Kang (Chung-Shan Medical University)

[P26-9-6] A-mangostin induces apoptosis and enhances cisplatin sensitivity in human cerivcal cancer stem cell

Yi-Hsien Hsieh¹, Hsieh Yi-Hsien², Lin Chu-Liang³ (1.Chung Shan Medical University, 2.Chung Shan Medical University, 3.Chung Shan Medical University)

[P26-9-7] Melatonin attenuates EGF-induced migration through downregulating Cathepsin S expression in human retinal pigment epithelial ARPE-19 cells

Yong-Syuan Chen¹, Yi-Hsien Hsieh² (1.Chung Shan Medical University, 2.Chung Shan Medical University)

[P26-9-8] Synergistic apoptotic effect of Norcantharidin combined with sorafenib in human RCC cells in vitro and in vivo

Shu-Ching Hsieh¹, Hsieh Shu-Ching², Hsieh Yi-Hsien³ (1.Chung Shan Medical University, 2.Chung Shan Medical University, 3.Chung Shan Medical University)

[P26-9-9] Tumor suppressor CYLD as a novel prognostic biomarker in primary breast cancer

Hirofumi Jono¹, Mitsuhiro Hayashi², Satoru Shinriki³, Chika Hirai⁴, Yukio Ando⁵, Hirotaka Iwase⁶, Hideyuki Saito⁷ (1.Kumamoto University Hospital, 2.National Cancer Center, 3.Kumamoto University Hospital, 4.Kumamoto University, 5.Kumamoto University, 6.Kumamoto University, 7.Kumamoto University Hospital)

[P26-9-10] A preliminary study for evaluation of docetaxel exposure and the occurrence of drug-induced toxicity in a Brazilian population

Marina Venzon Antunes¹, Suziane Raymundo², Ramon Magalhaes Mendonca Vilela³, Helena Kluck⁴, Camila Felix⁵, Victoria Vendramini Muller⁶, Paloma Ferraz⁷, Nicolas Peruzzo⁸, Natalia Bordin Andriguetti⁹, Rafael Linden¹⁰, Gilberto Schwartsmann¹¹ (1.Universidade Feevale, 2.Universidade Feevale, 3.Universidade Federal de Ciencias da Saude de Porto Alegre, 4.Hospital de Clinicas de Porto Alegre, 5.Hospital de Clinicas de Porto Alegre, 6.Universidade Feevale, 7.Universidade Feevale, 8.Hospital de Clinicas de Porto Alegre, 9.Universidade Feevale, 10.Universidade Feevale, 11.Hospital de Clinicas de Porto Alegre)

Session information

[P26-9] P26-9: Oncologic drugs (5): Pharmacokinetics, TDM practice