[O26-4] O26-4: Pharmacogenomics (2)

[O26-4-1] Small-dosing clinical study: pharmacokinetic, pharmacogenomic (SLCO2B1 and ABCG2), and interaction (atorvastatin and grapefruit Juice) profiles of five probes for OATP2B1 and BCRP

Yushi Kashihara¹, Ichiro Ieiri², Takashi Yoshikado³, Kazuya Maeda⁴, Masato Fukae⁵, Miyuki Kimura⁶, Takeshi Hirota⁷, Shunji Matsuki⁸, Shin Irie⁹, Noritomo Izumi¹⁰, Hiroyuki Kusuhara¹¹, Yuichi Sugiyama¹² (1.Kyushu University, 2.Kyushu University, 3.RIKEN Innovation Center, 4.The University of Tokyo, 5.Kyushu University, 6.Fukuoka Mirai Hospital Clinical Research Center, 7.Kyushu University, 8.Fukuoka Mirai Hospital Clinical Research Center, 9.Fukuoka Mirai Hospital Clinical Research Center, 10.Fukuoka Mirai Hospital Clinical Research Center, 11.The University of Tokyo, 12.RIKEN Innovation Center)

Keywords:Drug interactions, Pharmacokinetics, Pharmacogenomics, OATP2B1, BCRP