[O27-2] O27-2: Pharmacometrics (2)

[O27-2-1] Multiple-model optimization of sparse sample phenotyping of drug disposition utilizing population modeling

Ida Robertsen¹, Veronica Krogstad², Philip C. Angeles³, Linek Johnson⁴, Joran Hjelmesaeth⁵, Rune Sandbu⁶, Cecilia Karlsson⁷, Shalini Andersson⁸, TommyB Andersson⁹, Hege Christensen¹⁰, Anders Aasberg¹¹ (1.University of Oslo, 2.University of Oslo, 3.The Morbid Obesity Center and Vestfold Hospital Trust, 4.The Morbid Obesity Center and Vestfold Hospital Trust, 5.The Morbid Obesity Center and Vestfold Hospital Trust, 6.Vestfold Hospital Trust, 7.AstraZeneca Gothenburg, 8.AstraZeneca Gothenburg, 9.AstraZeneca Gothenburg, 10.University of Oslo, 11.Oslo University Hospital)

Keywords:pharmacokinetic population modeling, multiple-model optimal sampling, phenotyping, drug disposition