[P26-8] P26-8: Oncologic drugs (4): Pharmacokinetics, TDM practice

[P26-8-10] The relationship between hepatotoxicity and pazopanib trough plasma concentration in patients with renal cell carcinoma and soft tissue sarcoma

Takeshi Aoyama¹, Takako Karaki², Kazuyuki Ito³, Keiichi Azuma⁴, Koki Hashimoto⁵, Ryota Furutani⁶, Kazuyoshi Kawakami⁷, Kenichi Suzuki⁸, Kenji Nakano⁹, Junichi Tomomatsu¹⁰, Naoki Fukuda¹¹, Takeshi Yuasa¹², Erika Sugiyama¹³, Hitoshi Sato¹⁴, Shunji Takahashi¹⁵, Toshihiro Hama¹⁶ (1.The Cancer Institute Hospital, Japanese Foundation for Cancer Research, 2.The Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3.The Cancer Institute Hospital, Japanese Foundation for Cancer Research, 4.The Cancer Institute Hospital, Japanese Foundation for Cancer Research, 5.The Cancer Institute Hospital, Japanese Foundation for Cancer Research, 6.The Cancer Institute Hospital, Japanese Foundation for Cancer Research, 7.The Cancer Institute Hospital, Japanese Foundation for Cancer Research, 8.The Cancer Institute Hospital, Japanese Foundation for Cancer Research, 9.The Cancer Institute Hospital, Japanese Foundation for Cancer Research, 10.The Cancer Institute Hospital, Japanese Foundation for Cancer Research, 11.The Cancer Institute Hospital, Japanese Foundation for Cancer Research, 12.The Cancer Institute Hospital, Japanese Foundation for Cancer Research, 13.Showa University, 14.Showa University, 15.The Cancer Institute Hospital, Japanese Foundation for Cancer Research, 16.The Cancer Institute Hospital, Japanese Foundation for Cancer Research)

キーワード：hepatotoxicity Pazopanib, plasma trough concentrations, renal cell carcinoma , soft tissue sarcoma