[P27-10] P27-10: Pharmacokinetics and pharmacogenetics

[P27-10-7] Phenoconversion of CYP3A in chronic renal failure; what is the factor involved?

Yosuke Suzuki¹, Nanako Muraya², Takashi Fujioka³, Sato Fuminori⁴, Ryota Tanaka⁵, Kunihiro Matsumoto⁶, Yuhki Sato⁷, Keiko Ohno⁸, Hiromitsu Mimata⁹, Satoshi Kishino¹⁰, Hiroki Itoh¹¹ (1.Oita University Hospital, 2.Oita University Hospital, 3.Oita University Hospital, 4.Oita University, 5.Oita University Hospital, 6.Meiji Pharmaceutical University, 7.Oita University Hospital, 8.Meiji Pharmaceutical University, 9.Oita University, 10.Meiji Pharmaceutical University, 11.Oita University Hospital)

Keywords:phenoconversion, CYP3A, indoxyl sulfate, renal failure, 4β-hydroxycholesterol