[P27-8] P27-8: Assay and monitoring

[P27-8-1] A sensitive LC-MS/MS method for quantification of fluticasone propionate in human plasma after intranasal administration

Hiromi Shibasaki-Hirano¹, Rena Adachi², Aya Yamagata³, Ryohei Hirano⁴, Akitomo Yokokawa⁵, Kaori Hosoda⁶, Aki Obara⁷, Kazuo Ishii⁸, Takashi Furuta⁹ (1.Tokyo University of Pharmacy and Life Sciences, 2.Tokyo University of Pharmacy and Life Sciences, 3.Tokyo University of Pharmacy and Life Sciences, 4.Tokyo University of Pharmacy and Life Sciences, 5.Tokyo University of Pharmacy and Life Sciences, 6.Kyorin University, 7.Kyorin University, 8.Kyorin University, 9.Tokyo University of Pharmacy and Life Sciences)

キーワード：fluticasone propionate, nasal spray, LC-MS/MS, pharmacokinetics, plasma concentration