[S-12] S-12: TDM for central nervous system drugs

[S-12-3] Lamotrigine and valproate drug interactions — the role of pharmacogenomics

Iva Klarica Domjanovic¹, Mila Lovric², Zeljka Petelin Gadze³, Lana Ganoci⁴, Vladimir Trkulja⁵, Nada Bozina⁶ (1.Agency for Medicinal Products and Medical Devices, 2.University Hospital Centre Zagreb, 3.University Hospital Centre Zagreb, 4.University Hospital Centre Zagreb, 5.School of Medicine, University of Zagreb, 6.University Hospital Centre Zagreb)

キーワード：lamotrigine, valproate, UGT enzymes, ABCG2, genes polymorphisms