IATDMCT 2017

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Symposium

[S-12] S-12: TDM for central nervous system drugs

Tue. Sep 26, 2017 10:30 AM - 12:00 PM Room E (1F)

Chairs: Kiyofumi Yamada, Japan / Philip Nicholaou Patsalos, UK

[S-12-5] Neonatal PBPK modeling of morphine disposition with OCT1 transporter developmental expression

Chie Emoto1, David Hahn2, Alexander A. Vinks3, Tsuyoshi Fukuda4 (1.Cincinnati Children's Hospital Medical Center, 2.Cincinnati Children's Hospital Medical Center, 3.Cincinnati Children's Hospital Medical Center, 4.Cincinnati Children's Hospital Medical Center)

Keywords:Neonates, Ontogeny, OCT1 transporter, PBPK modeling, Morphine

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