Session information

Session

[Session 13] In silico PBPK Modeling & Simulation of P450s

Mon. Jun 15, 2015 9:00 AM - 11:00 AM Hall A (International Conference Room 1F)

Chair:Koji Chiba (Laboratory of Clinical Pharmacology, Yokohama University of Pharmacy), Chair:Aleksandra Galetin (Centre for Applied Pharmacokinetic Research, Manchester Pharmacy School, University of Manchester)

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[Session 13-1] MODELLING AND SIMULATION OF TRANSPORTER-METABOLISM INTERPLAY AND CORRESPONDING DRUG-DRUG INTERACTIONS

^○Aleksandra Galetin (Centre for Applied Pharmacokinetic Research, Manchester Pharmacy School, University of Manchester)

[Session 13-2] Kinetic interpretation of complex drug-drug interaction on both P450s and membrane transporters: Importance of knowing rate-determining process

^○Yuichi Sugiyama (Sugiyama Laboratory, RIKEN Innovation Center, RIKEN)

[Session 13-3] Variability of P450 activity for prediction of drug exposure in human

^○Koji Chiba (Laboratory of Clinical Pharmacology, Yokohama University of Pharmacy)

[Session 13-4] Evaluation and Modeling of Intestinal Contribution in Pharmacokinetics

^○Akihiro Hisaka (Geriatric Pharmacolgy and Therapeatics, Graduate School of Pharmaceutical Sciences, Chiba University)

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