Symposium

15. Pesticides, GM Crops, Resistance and Toxicology

[15-1] Transitioning Insecticide Science Technologies for the Development of Novel Chemistries

Mon. Aug 26, 2024 1:30 PM - 6:15 PM Room F

Chair: Daniel Swale (University of Florida), Troy D Anderson (University of Nebraska), Yoshihisa Ozoe (Shimane University)

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1:30 PM - 2:00 PM

[15-1-01] Interaction of recombinantly expressed fall armyworm ABCC2 variants with Bt Cry toxins unveils resistance mutations in extracellular loops impairing pore formation

*Ralf Nauen¹, Laura Franz, Bettina Lueke, Dominik Schwarz, Jaishree Chittoor, Andrew Dunn, Sunran Kim (1. Bayer AG, Crop Science Division (Germany))

2:00 PM - 2:15 PM

[15-1-02] Estimation of the mode of action of a new insecticide candidate, NNI-2101, by using the genomic analysis of the mutant Caenorhabditis elegans

*Motofumi Nakano¹, Ikki Yonemura¹, Akiyuki Suwa¹ (1. NIHON NOHYAKU CO., LTD. (Japan))

2:15 PM - 2:30 PM

[15-1-03] Pyrethrins act as feeding deterrents by irritating the insect oral taste organs through the intrinsic neurotoxic actions

*Takeshi Kojima¹, Seiji Yamato¹ (1. Health & Crop Sciences Research Laboratory, Sumitomo Chemical Co., Ltd. (Japan))

2:30 PM - 2:45 PM

[15-1-04] Verification of the binding site of fluralaner in vivo using CRISPR/Cas9

*Chunqing Zhao¹ (1. Nanjing Agricultural University (China))

2:45 PM - 3:00 PM

[15-1-05] Chordotonal organ modulators as insecticides and beyond

Xiaomu Qiao², Xiaoyu Zhang¹, Jianhui Qin¹, Ye Zhao¹, *Jia Huang¹ (1. Zhejiang University (China), 2. Xianghu Laboratory (China))

3:00 PM - 3:15 PM

[15-1-06] The Mode of Action of Insecticidal Alkylsulfones

*Andrew James Crossthwaite¹ (1. Syngenta (Switzerland))

3:15 PM - 3:30 PM

[15-1-07] Molecular understanding of target site actions of neonicotinoid insecticides

*Kazuhiko Matsuda¹ (1. Kindai University (Japan))

Coffee Break (3:30 PM - 4:15 PM)

4:15 PM - 4:30 PM

[15-1-08] Functional in vivo tools for the characterization of novel targets and the development of selective insecticides

*Stefanos Mastis^1,2, John Vontas^2,3 (1. University of Crete (Greece), 2. Institute of Molecular Biology and Biotechnology of the Foundation for Research and Technology Hellas (IMBB-FORTH) (Greece), 3. Agricultural University of Athens (Greece))

4:30 PM - 4:45 PM

[15-1-09] Functionality of mosquito ABC transporters and strategies to improve insecticide delivery

*Troy D Anderson¹, Heather M Hernandez¹, Xi Xian Ng¹, Leslie C Rault¹, Ellis J Johnson¹ (1. University of Nebraska (United States of America))

4:45 PM - 5:00 PM

[15-1-10] Development of novel mechanism aphicides to prevent horizontal transmission of non-persistent plant pathogens

*Daniel Swale¹ (1. University of Florida (United States of America))

5:00 PM - 5:15 PM

[15-1-11] Exploring cys-loop ligand-gated ion channels, superfamilies of pesticide targets

Eleanor L. Mitchell³, Emily B. Armstrong¹, Franco Viscarra¹, Isabel Bermudez¹, Joseph Hawkins², Jim A. Goodchild², *Andrew Jones¹ (1. Oxford Brookes University (UK), 2. Syngenta (UK), 3. University of Leeds (UK))

5:15 PM - 5:30 PM

[15-1-12] Molecular mechanisms of gene expression variation associated with resistance in a polyphagous pest

*Thomas Van Leeuwen¹, Mathijs Herpoel¹, Meiyuan Ji², Marilou Vandenhole¹, Berdien De Beer¹, Sander De Rouck¹, René Feyereisen¹, Richard M Clark² (1. Ghent University (Belgium), 2. University of Utah (United States of America))

5:30 PM - 5:45 PM

[15-1-13] Identification and characterization of cytochrome p450s putatively associated with fluvalinate resistance in Varroa mites

*Si Hyeock Lee¹ (1. Seoul National University (Korea))

5:45 PM - 6:00 PM

[15-1-14] The genomics of adaptation to natural and synthetic xenobiotics in the aphid Myzus persicae

*Chris Bass¹ (1. University of Exeter (UK))

6:00 PM - 6:15 PM

[15-1-15] Identifying determinants of the antagonism of γ-aminobutyric acid-gated chloride channels by fluralaner

*Yoshihisa Ozoe¹ (1. Shimane University (Japan))

Session information