*Miki Ohta¹, Rika Okamoto², Kimie Sai³, Takuya Imatoh⁴, Susumu Wakabayashi^5,8, Shoko Suzuki⁶, Susumu Ogawa⁷, Ryoma Seto⁸, Noriaki Arakawa³ (1. The University of Tokyo Hospital, 2. Translational Research Center for Medical Innovation, Foundation for Biomedical Research and Innovation at Kobe, 3. National Institute of Health Sciences, 4. Faculty of Pharmaceutical Sciences, Fukuoka University, 5. Kyorin University Hospital, 6. International Institute for Advanced Studies, 7. Pharmaceutical Safety Bureau, Ministry of Health, Labour and Welfare, 8. Faculty of Healthcare, Tokyo Healthcare University)

*Susumu Ogawa¹, Haruka Iwai¹, Yumiko Nomura¹ (1. Pharmaceutical Safety Bureau, Ministry of Health, Labour and Welfare)

*Kimie Sai¹ (1. National Insititute of Health Sciences)

*Takuya Imatoh¹ (1. Faculty of Pharmaceutical Sciences, Fukuoka University)

*Miki Ohta¹, Rika Okamoto² (1. The University of Tokyo Hospital, 2. Translational Research Center for Medical Innovation, Foundation for Biomedical Research and Innovation at Kobe)

*Rika Okamoto¹ (1. Translational Research Center for Medical Innovation)

*Susumu Wakabayashi^1,2, Ryoma Seto² (1. Kyorin University Hospital, 2. Faculty of Healthcare, Tokyo Healthcare University)