[MO-22] Presentation Awards
Impact of onset-to-intervention time in Acute Limb Ischemia
【Objectives】Acute limb ischemia (ALI) is a sudden decrease of limb perfusion that has a potential threat of life and limb viability. It is generally accepted intervention within 6 hours from the onset can lead to limb salvage. However, there are only few reports about the onset-to-intervention time.
【Methods】We retrospectively analyzed 28 patients who were treated for ALI from January 2019 to November 2018. We evaluated the relationship between onset-to-intervention time and composite events including death, limb loss and re-intervention.
【Results】A total of 28 patients were enrolled in this study. Totally 8 patients (28.6%)occurred composite events within 1 year. Onset-to-intervention time was significantly shorter in patients without composite events(24.3±33.5hrs vs 56.6±51.8hrs p=0.041). Onset-to-intervention time were divided into three groups; 0-6hrs, 6-24hrs, and over 24 hrs. Composite event-free survival were similar between 0-6hrs and 6-24hrs groups, and tended to be lower in the over 24 hrs group (85.7%, 80.5%, and 50.0%, respectively)(Figure 1A). By dividing into two groups (0-24hrs and over 24 hrs), composite event-free survival was significantly higher in the 0-24 hrs group (83.0% vs 50.0%, log rank p = 0.045)(Figure 1B).
【Conclusions】Onset-to-intervention time within 24 hrs would be acceptable for composite event-free survival in ALI.
【Methods】We retrospectively analyzed 28 patients who were treated for ALI from January 2019 to November 2018. We evaluated the relationship between onset-to-intervention time and composite events including death, limb loss and re-intervention.
【Results】A total of 28 patients were enrolled in this study. Totally 8 patients (28.6%)occurred composite events within 1 year. Onset-to-intervention time was significantly shorter in patients without composite events(24.3±33.5hrs vs 56.6±51.8hrs p=0.041). Onset-to-intervention time were divided into three groups; 0-6hrs, 6-24hrs, and over 24 hrs. Composite event-free survival were similar between 0-6hrs and 6-24hrs groups, and tended to be lower in the over 24 hrs group (85.7%, 80.5%, and 50.0%, respectively)(Figure 1A). By dividing into two groups (0-24hrs and over 24 hrs), composite event-free survival was significantly higher in the 0-24 hrs group (83.0% vs 50.0%, log rank p = 0.045)(Figure 1B).
【Conclusions】Onset-to-intervention time within 24 hrs would be acceptable for composite event-free survival in ALI.