[MO-61] Presentation Awards
A Successfully Intervention for a Case of Venous Thrombosis and Pulmonary Embolization with Anti-thrombin Ⅲ Deficiency.
A 20 years old man without any medical past history, whose father and paternal relatives had thromboembolic diseases complained short of breath and severe pain in his left thigh. Contrast computed tomography revealed filling defect in bilateral pulmonary artery indicating pulmonary embolization (PE), and lower limb duplex ultrasound detected venous thrombosis (VT) in left iliac vein. Screening laboratory test for coagulation abnormality showed low activity of anti-thrombinⅢ only. He met the criteria of probable congenital anti-thrombinⅢ deficiency (the result of genetic test was not available yet).
We had prescriced oral anticoagulation agent and done intravenous thrombolysis after temporary inferior vena cava (IVC) filter implantation. However, VT didn’t disappear completely after the treatment, we performed intravenous intervention: thrombo-aspiration and catheter directed thrombolysis (CDT) with urokinase for five days. Follow-up venous angiography showed that VT had almost disappeared, and we have observed the patient for four months without any recurrence of thromboembolism.
We experienced a rare case of VT and PE with anti-thrombinⅢ deficiency, which was successfully treated with intravenous intervention.
We had prescriced oral anticoagulation agent and done intravenous thrombolysis after temporary inferior vena cava (IVC) filter implantation. However, VT didn’t disappear completely after the treatment, we performed intravenous intervention: thrombo-aspiration and catheter directed thrombolysis (CDT) with urokinase for five days. Follow-up venous angiography showed that VT had almost disappeared, and we have observed the patient for four months without any recurrence of thromboembolism.
We experienced a rare case of VT and PE with anti-thrombinⅢ deficiency, which was successfully treated with intravenous intervention.