[G] Biomaterials Development and Clinics

[219] Regulation of balance in proliferation and calcification of MC3T3-E1 on Ti with nano-topographical patterned surface fabricated by femtosecond laser

*Peng CHEN¹, Naoki SHINOHARA², Togo SHINONAGA³, Yuji SATO⁴, Masahiro TSUKAMOTO⁴, Maki ASHIDA¹, Takao HANAWA¹ (1. TMDU, 2. Graduate School, Osaka Univ., 3. Okayama Univ., 4. Osaka Univ.)

Keywords:Titanium、Nano-topography、Femtosecond laser、Preosteoblast、Calcification

Ti with nano-topographical patterned surfaces were fibricated by femtosecon laser irradiation. An improved balance in proliferation and calcification of preosteoblast was achieved.