[B-PT26_2AM1] 古代ゲノム学

[BPT26-04] 祖先的前口動物の形態形成遺伝子セットの復元

*遠藤 一佳¹、スティアマルガ デフィン¹、清水 啓介¹ (1.東大・理・地惑)

キーワード：古代ゲノム, 多細胞動物, 発生進化学, シグナル伝達遺伝子, カンブリア爆発, 冠輪動物

Recently, a draft genome sequence of the pearl oyster Pinctada fucata was reported, enabling to infer a possible evolutionary scenario of the gene sets that are important for body plan formation in protostomes including both lophotrochozoans and ecdysozoans. We report the results of phylogenetic character mapping carried out for the gene families that encode developmental signaling ligands (Fgf, Hedgehog, PDGF/VEGF, TGF-b, and Wnt families) to reconstruct possible copy numbers of signaling molecule-coding genes for hypothetical ancestral protostomes. Our reconstruction suggests that P. fucata retains the ancestral protostome gene complement, providing further justifications for the use of this taxon as a model organism for developmental genomics research.