4:30 PM - 4:45 PM
[BPT26-02] Understanding the relationship between rise of oxygen and gene expression of cyanobacterial antioxidant enzymes
Keywords:rise of oxygen, antioxidant enzymes, cyanobacteria
Here we focused on the changes in the expression of genes encoding antioxidant enzymes of cyanobacteria through history. Changes in environmental O2 levels must have affected the production of reactive oxygen species, which in turn affected antioxidant gene expression. Gene expression is regulated by the nucleotide sequence in the promoter regions. Thus we hypothesized that the ancestral promoter sequences of the antioxidant enzymes may reflect the environmental O2 levels at the time the ancestor existed. In this study, we resurrected the ancestral promoter sequences of the antioxidant enzymes, and discuss its relationship to the O2 evolution through time. In this presentation, we will first introduce recent models of the atmospheric O2 evolution through Earth's history, then we will report our progress in resurrecting ancestral promoter sequences of cyanobacterial antioxidant enzymes.