3:30 PM - 3:45 PM
[MIS14-13] The reversible TCA cycle in thermophilic chemolithotrophs
Keywords:TCA cycle, thermophile
A deeply-branching, chemolithotrophic and thermophilic bacterium, Thermosulfidibacter takaii grows with hydrogen oxidation coupled with sulfur reduction under both autotrophic and mixotrophic growth conditions. We identified the reversible TCA cycle with citrate synthase in T. takaii that functioned reductively for carbon fixation under autotrophic condition and as bifurcatated pathways under mixotrophic conditions (Nunoura et al. 2018). Similar reversible TCA cycle was also found in a facultatively chemolithoautotrophic deltaproteobacterium Desulfurella acetivorans (Mall et al. 2018). I will introduce the previously unseen reversible TCA cycle and its impacts on the environmental microbiology and the discussions related to the origin of life.